Skip to main content
Fig. 9 | Clinical Epigenetics

Fig. 9

From: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

Fig. 9

a Western blot of EMT and invasion related proteins: E-cadherin, N-cadherin, MMP-2, MMP-3, and MMP-9. MC4040 and MC4041 were used at 20 μM for 48 h. The densitometry quantitation is indicated for each band normalized for actin band. b Matrigel invasion assay of U-87 and GL1 cells untreated (ctr) and treated with 20 μM MC4040 or MC4041 for 48 h. c Migrated cells were counted in five random fields. Three independent experiments were performed, and the results are presented with the mean ± SD **p < 0.01

Back to article page
\