Skip to main content
Fig. 2 | Clinical Epigenetics

Fig. 2

From: RETRACTED ARTICLE: Dissecting the role of novel EZH2 inhibitors in primary glioblastoma cell cultures: effects on proliferation, epithelial-mesenchymal transition, migration, and on the pro-inflammatory phenotype

Fig. 2

a MC4040 (carbon atoms in black) docked conformation into PCR2. Only surface (blue) and names of residues within 5 Å are displayed. Close contact surfaces with the pyridone moiety are coloured in pink. Close contact surfaces with the pyrrole-3-carboxamide central group are coloured in magenta and contact surfaces with the piperidine heterocycle are coloured in yellow. Residue numbering is taken from the 6b3w complex. b MC4041 (carbon atoms in dark grey) docked conformation into PCR2. Only surface (blue) and names of residues within 5 Å are displayed. Close contact surfaces with the pyridone moiety are coloured in pink. Close contact surfaces with the pyrrole-3-carboxamide central group are coloured in magenta and contact surfaces with the piperidine heterocycle are coloured in orange. Residue numbering are taken from the 6b3w complex

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us