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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study

Fig. 5

Independent validation of TriMeth in plasma. a Methylation-specific ddPCR was performed on cfDNA purified from plasma of CRC patients and controls (validation cohort) to detect methylated C9orf50, KCNQ5, and CLIP4. b Sensitivity and specificity of the TriMeth tes. c UICC stage-stratified sensitivity of TriMeth. Error bars represent 95% CI. ddPCR droplet digital PCR, CRC colorectal cancer, UICC Union for International Cancer Control

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Clinical Epigenetics

ISSN: 1868-7083

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