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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Novel DNA methylation biomarkers show high sensitivity and specificity for blood-based detection of colorectal cancer—a clinical biomarker discovery and validation study

Fig. 3

DNA methylation of C9orf50, KCNQ5, and CLIP4. a DNA methylation levels (Infinium HumanMethylation450K BeadChip® array data) of the three markers C9orf50, KCNQ5, and CLIP4 in 571 individual CRC tumours, 556 PBL samples, and 4111 samples from other cancer types. Each of the three markers are hypermethylated (β-value > 0.35) in > 97% of CRC tumours. b Correlation of DNA methylation levels in CRC tissue of the C9orf50, KCNQ5, and CLIP4 markers. HNSCC head and neck squamous cell carcinoma, BCL B-Cell lymphoma, AML acute myeloid leukaemia

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