Methylation, hydroxymethylation and expression of OXT across Braak staging. Regressed OXT expression values and average regressed 5mC and 5hmC values of 10 and 9 overlapping probes within the OXT DMR are shown. Regressed values were generated by taking the residuals of a model fitted with the covariates age, gender, and 5 surrogate variables, but excluding the predictor of interest AD diagnosis. Error bars represent mean ± SEM. N = 76 for each line.