Figure 2.
From: Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood
Methylation, hydroxymethylation and expression of OXT across Braak staging. Regressed OXT expression values and average regressed 5mC and 5hmC values of 10 and 9 overlapping probes within the OXT DMR are shown. Regressed values were generated by taking the residuals of a model fitted with the covariates age, gender, and 5 surrogate variables, but excluding the predictor of interest AD diagnosis. Error bars represent mean ± SEM. N = 76 for each line.