TY - JOUR AU - Vliet-Ostaptchouk, J. V. AU - Nuotio, M. -. L. AU - Slagter, S. N. AU - Doiron, D. AU - Fischer, K. AU - Foco, L. PY - 2014 DA - 2014// TI - The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies JO - BMC Endocr Disord VL - 14 UR - https://doi.org/10.1186/1472-6823-14-9 DO - 10.1186/1472-6823-14-9 ID - Vliet-Ostaptchouk2014 ER - TY - JOUR AU - Hinnouho, G. -. M. AU - Czernichow, S. AU - Dugravot, A. AU - Nabi, H. AU - Brunner, E. J. AU - Kivimaki, M. PY - 2015 DA - 2015// TI - Metabolically healthy obesity and the risk of cardiovascular disease and type 2 diabetes: the Whitehall II cohort study JO - Eur Heart J VL - 36 UR - https://doi.org/10.1093/eurheartj/ehu123 DO - 10.1093/eurheartj/ehu123 ID - Hinnouho2015 ER - TY - JOUR AU - Tchernof, A. AU - Després, J. -. P. PY - 2013 DA - 2013// TI - Pathophysiology of human visceral obesity: an update JO - Physiol Rev VL - 93 UR - https://doi.org/10.1152/physrev.00033.2011 DO - 10.1152/physrev.00033.2011 ID - Tchernof2013 ER - TY - JOUR AU - Grundy, S. M. AU - Cleeman, J. I. AU - Daniels, S. R. AU - Donato, K. A. AU - Eckel, R. H. AU - Franklin, B. A. PY - 2005 DA - 2005// TI - Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement JO - Circulation. VL - 112 UR - https://doi.org/10.1161/CIRCULATIONAHA.105.169404 DO - 10.1161/CIRCULATIONAHA.105.169404 ID - Grundy2005 ER - TY - JOUR AU - Hamer, M. AU - Stamatakis, E. PY - 2012 DA - 2012// TI - Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality JO - J Clin Endocrinol Metab VL - 97 UR - https://doi.org/10.1210/jc.2011-3475 DO - 10.1210/jc.2011-3475 ID - Hamer2012 ER - TY - JOUR AU - Ghosh, S. AU - Bouchard, C. PY - 2017 DA - 2017// TI - Convergence between biological, behavioural and genetic determinants of obesity JO - Nat Rev Genet VL - 18 UR - https://doi.org/10.1038/nrg.2017.72 DO - 10.1038/nrg.2017.72 ID - Ghosh2017 ER - TY - JOUR AU - Pigeyre, M. AU - Yazdi, F. T. AU - Kaur, Y. AU - Meyre, D. PY - 2016 DA - 2016// TI - Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity JO - Clin Sci VL - 130 UR - https://doi.org/10.1042/CS20160136 DO - 10.1042/CS20160136 ID - Pigeyre2016 ER - TY - JOUR AU - Crujeiras, A. B. AU - Diaz-Lagares, A. AU - Moreno-Navarrete, J. M. AU - Sandoval, J. AU - Hervas, D. AU - Gomez, A. PY - 2016 DA - 2016// TI - Genome-wide DNA methylation pattern in visceral adipose tissue differentiates insulin-resistant from insulin-sensitive obese subjects JO - Transl Res VL - 178 UR - https://doi.org/10.1016/j.trsl.2016.07.002 DO - 10.1016/j.trsl.2016.07.002 ID - Crujeiras2016 ER - TY - JOUR AU - Toro-Martín, J. AU - Guénard, F. AU - Tchernof, A. AU - Deshaies, Y. AU - Pérusse, L. AU - Hould, F. S. PY - 2016 DA - 2016// TI - Methylation quantitative trait loci within the TOMM20 gene are associated with metabolic syndrome-related lipid alterations in severely obese subjects JO - Diabetol Metab Syndr VL - 8 UR - https://doi.org/10.1186/s13098-016-0171-3 DO - 10.1186/s13098-016-0171-3 ID - Toro-Martín2016 ER - TY - JOUR AU - Toro-Martín, J. AU - Guénard, F. AU - Tchernof, A. AU - Deshaies, Y. AU - Pérusse, L. AU - Biron, S. PY - 2016 DA - 2016// TI - A CpG-SNP located within the ARPC3 gene promoter is associated with hypertriglyceridemia in severely obese patients JO - Ann Nutr Metab VL - 68 UR - https://doi.org/10.1159/000445358 DO - 10.1159/000445358 ID - Toro-Martín2016 ER - TY - JOUR AU - Guénard, F. AU - Tchernof, A. AU - Deshaies, Y. AU - Pérusse, L. AU - Biron, S. AU - Lescelleur, O. PY - 2014 DA - 2014// TI - Differential methylation in visceral adipose tissue of obese men discordant for metabolic disturbances JO - Physiol Genomics VL - 46 UR - https://doi.org/10.1152/physiolgenomics.00160.2013 DO - 10.1152/physiolgenomics.00160.2013 ID - Guénard2014 ER - TY - JOUR AU - Ribel-Madsen, R. AU - Fraga, M. F. AU - Jacobsen, S. AU - Bork-Jensen, J. AU - Lara, E. AU - Calvanese, V. PY - 2012 DA - 2012// TI - Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes. Dahlman IA, editor JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0051302 DO - 10.1371/journal.pone.0051302 ID - Ribel-Madsen2012 ER - TY - JOUR AU - Turcot, V. AU - Tchernof, A. AU - Deshaies, Y. AU - Pérusse, L. AU - Bélisle, A. AU - Marceau, S. PY - 2012 DA - 2012// TI - LINE-1 methylation in visceral adipose tissue of severely obese individuals is associated with metabolic syndrome status and related phenotypes JO - Clin Epigenetics VL - 4 UR - https://doi.org/10.1186/1868-7083-4-10 DO - 10.1186/1868-7083-4-10 ID - Turcot2012 ER - TY - JOUR AU - Crujeiras, A. B. AU - Diaz-Lagares, A. AU - Sandoval, J. AU - Milagro, F. I. AU - Navas-Carretero, S. AU - Carreira, M. C. PY - 2017 DA - 2017// TI - DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep41903 DO - 10.1038/srep41903 ID - Crujeiras2017 ER - TY - JOUR AU - Guénard, F. AU - Deshaies, Y. AU - Hould, F. -. S. AU - Lebel, S. AU - Tchernof, A. AU - Marceau, P. PY - 2016 DA - 2016// TI - Use of blood as a surrogate model for the assessment of visceral adipose tissue methylation profiles associated with the metabolic syndrome in men JO - J Mol Genet Med VL - 10 UR - https://doi.org/10.4172/1747-0862.1000198 DO - 10.4172/1747-0862.1000198 ID - Guénard2016 ER - TY - JOUR AU - Ravlić, S. AU - Škrobot Vidaček, N. AU - Nanić, L. AU - Laganović, M. AU - Slade, N. AU - Jelaković, B. PY - 2018 DA - 2018// TI - Mechanisms of fetal epigenetics that determine telomere dynamics and health span in adulthood JO - Mech Ageing Dev VL - 174 UR - https://doi.org/10.1016/j.mad.2017.08.014 DO - 10.1016/j.mad.2017.08.014 ID - Ravlić2018 ER - TY - JOUR AU - Cheng, Z. AU - Zheng, L. AU - Almeida, F. A. PY - 2018 DA - 2018// TI - Epigenetic reprogramming in metabolic disorders: nutritional factors and beyond JO - J Nutr Biochem VL - 54 UR - https://doi.org/10.1016/j.jnutbio.2017.10.004 DO - 10.1016/j.jnutbio.2017.10.004 ID - Cheng2018 ER - TY - JOUR AU - Salvestrini, V. AU - Sell, C. AU - Lorenzini, A. PY - 2019 DA - 2019// TI - Obesity may accelerate the aging process JO - Front Endocrinol (Lausanne) VL - 10 UR - https://doi.org/10.3389/fendo.2019.00266 DO - 10.3389/fendo.2019.00266 ID - Salvestrini2019 ER - TY - JOUR AU - Christensen, B. C. AU - Houseman, E. A. AU - Marsit, C. J. AU - Zheng, S. AU - Wrensch, M. R. AU - Wiemels, J. L. PY - 2009 DA - 2009// TI - Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CPG island context. Schübeler D, editor JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000602 DO - 10.1371/journal.pgen.1000602 ID - Christensen2009 ER - TY - JOUR AU - Horvath, S. AU - Zhang, Y. AU - Langfelder, P. AU - Kahn, R. S. AU - Boks, M. P. M. AU - Eijk, K. PY - 2012 DA - 2012// TI - Aging effects on DNA methylation modules in human brain and blood tissue JO - Genome Biol VL - 13 UR - https://doi.org/10.1186/gb-2012-13-10-r97 DO - 10.1186/gb-2012-13-10-r97 ID - Horvath2012 ER - TY - JOUR AU - Horvath, S. PY - 2013 DA - 2013// TI - DNA methylation age of human tissues and cell types JO - Genome Biol VL - 14 UR - https://doi.org/10.1186/gb-2013-14-10-r115 DO - 10.1186/gb-2013-14-10-r115 ID - Horvath2013 ER - TY - JOUR AU - Hannum, G. AU - Guinney, J. AU - Zhao, L. AU - Zhang, L. AU - Hughes, G. AU - Sadda, S. PY - 2013 DA - 2013// TI - Genome-wide methylation profiles reveal quantitative views of human aging rates JO - Mol Cell VL - 49 UR - https://doi.org/10.1016/j.molcel.2012.10.016 DO - 10.1016/j.molcel.2012.10.016 ID - Hannum2013 ER - TY - JOUR AU - Levine, M. E. AU - Lu, A. T. AU - Quach, A. AU - Chen, B. H. AU - Assimes, T. L. AU - Bandinelli, S. PY - 2018 DA - 2018// TI - An epigenetic biomarker of aging for lifespan and healthspan JO - Aging (Albany NY) VL - 10 UR - https://doi.org/10.18632/aging.101414 DO - 10.18632/aging.101414 ID - Levine2018 ER - TY - JOUR AU - Horvath, S. AU - Erhart, W. AU - Brosch, M. AU - Ammerpohl, O. AU - Schonfels, W. AU - Ahrens, M. PY - 2014 DA - 2014// TI - Obesity accelerates epigenetic aging of human liver JO - Proc Natl Acad Sci VL - 111 UR - https://doi.org/10.1073/pnas.1412759111 DO - 10.1073/pnas.1412759111 ID - Horvath2014 ER - TY - JOUR AU - Ling, C. AU - Rönn, T. PY - 2019 DA - 2019// TI - Epigenetics in human obesity and type 2 diabetes JO - Cell Metab VL - 29 UR - https://doi.org/10.1016/j.cmet.2019.03.009 DO - 10.1016/j.cmet.2019.03.009 ID - Ling2019 ER - TY - STD TI - de Toro-Martín J, Guénard F, Tchernof A, Pérusse L, Marceau S, Vohl, M-C. Polygenic risk score for predicting weight loss after bariatric surgery. JCI Insight. 2018;3(17):e122011. ID - ref26 ER - TY - JOUR AU - Ahrens, M. AU - Ammerpohl, O. AU - Schönfels, W. AU - Kolarova, J. AU - Bens, S. AU - Itzel, T. PY - 2013 DA - 2013// TI - DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery JO - Cell Metab VL - 18 UR - https://doi.org/10.1016/j.cmet.2013.07.004 DO - 10.1016/j.cmet.2013.07.004 ID - Ahrens2013 ER - TY - JOUR AU - Horvath, S. AU - Gurven, M. AU - Levine, M. E. AU - Trumble, B. C. AU - Kaplan, H. AU - Allayee, H. PY - 2016 DA - 2016// TI - An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease JO - Genome Biol VL - 17 UR - https://doi.org/10.1186/s13059-016-1030-0 DO - 10.1186/s13059-016-1030-0 ID - Horvath2016 ER - TY - JOUR AU - Thompson, R. F. AU - Atzmon, G. AU - Gheorghe, C. AU - Liang, H. Q. AU - Lowes, C. AU - Greally, J. M. PY - 2010 DA - 2010// TI - Tissue-specific dysregulation of DNA methylation in aging JO - Aging Cell VL - 9 UR - https://doi.org/10.1111/j.1474-9726.2010.00577.x DO - 10.1111/j.1474-9726.2010.00577.x ID - Thompson2010 ER - TY - JOUR AU - Huang, Y. -. T. T. AU - Chu, S. AU - Loucks, E. B. AU - Lin, C. -. L. L. AU - Eaton, C. B. AU - Buka, S. L. PY - 2016 DA - 2016// TI - Epigenome-wide profiling of DNA methylation in paired samples of adipose tissue and blood JO - Epigenetics. VL - 11 UR - https://doi.org/10.1080/15592294.2016.1146853 DO - 10.1080/15592294.2016.1146853 ID - Huang2016 ER - TY - JOUR AU - Nevalainen, T. AU - Kananen, L. AU - Marttila, S. AU - Jylhävä, J. AU - Mononen, N. AU - Kähönen, M. PY - 2017 DA - 2017// TI - Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals JO - Clin Epigenetics VL - 9 UR - https://doi.org/10.1186/s13148-016-0301-7 DO - 10.1186/s13148-016-0301-7 ID - Nevalainen2017 ER - TY - JOUR AU - Grundy, S. M. AU - Williams, C. AU - Vega, G. L. PY - 2018 DA - 2018// TI - Upper body fat predicts metabolic syndrome similarly in men and women JO - Eur J Clin Investig VL - 48 UR - https://doi.org/10.1111/eci.12941 DO - 10.1111/eci.12941 ID - Grundy2018 ER - TY - JOUR AU - Gensous, N. AU - Franceschi, C. AU - Santoro, A. AU - Milazzo, M. AU - Garagnani, P. AU - Bacalini, M. G. PY - 2019 DA - 2019// TI - The impact of caloric restriction on the epigenetic signatures of aging JO - Int J Mol Sci VL - 20 UR - https://doi.org/10.3390/ijms20082022 DO - 10.3390/ijms20082022 ID - Gensous2019 ER - TY - JOUR AU - Rönn, T. AU - Volkov, P. AU - Davegårdh, C. AU - Dayeh, T. AU - Hall, E. AU - Olsson, A. H. PY - 2013 DA - 2013// TI - A six months exercise intervention influences the genome-wide dna methylation pattern in human adipose tissue. Greally JM, editor JO - PLoS Genet VL - 9 UR - https://doi.org/10.1371/journal.pgen.1003572 DO - 10.1371/journal.pgen.1003572 ID - Rönn2013 ER - TY - JOUR AU - Tchkonia, T. AU - Morbeck, D. E. AU - Zglinicki, T. AU - Deursen, J. AU - Lustgarten, J. AU - Scrable, H. PY - 2010 DA - 2010// TI - Fat tissue, aging, and cellular senescence JO - Aging Cell VL - 9 UR - https://doi.org/10.1111/j.1474-9726.2010.00608.x DO - 10.1111/j.1474-9726.2010.00608.x ID - Tchkonia2010 ER - TY - JOUR AU - Lakowa, N. AU - Trieu, N. AU - Flehmig, G. AU - Lohmann, T. AU - Schön, M. R. AU - Dietrich, A. PY - 2015 DA - 2015// TI - Telomere length differences between subcutaneous and visceral adipose tissue in humans JO - Biochem Biophys Res Commun VL - 457 UR - https://doi.org/10.1016/j.bbrc.2014.12.122 DO - 10.1016/j.bbrc.2014.12.122 ID - Lakowa2015 ER - TY - JOUR AU - Sun, K. AU - Kusminski, C. M. AU - Scherer, P. E. PY - 2011 DA - 2011// TI - Adipose tissue remodeling and obesity JO - J Clin Invest VL - 121 UR - https://doi.org/10.1172/JCI45887 DO - 10.1172/JCI45887 ID - Sun2011 ER - TY - JOUR AU - Biertho, L. AU - Lebel, S. AU - Marceau, S. AU - Hould, F. -. S. S. AU - Julien, F. AU - Biron, S. PY - 2016 DA - 2016// TI - Biliopancreatic diversion with duodenal switch: surgical technique and perioperative care JO - Surg Clin North Am VL - 96 UR - https://doi.org/10.1016/j.suc.2016.03.012 DO - 10.1016/j.suc.2016.03.012 ID - Biertho2016 ER - TY - JOUR AU - Aryee, M. J. AU - Jaffe, A. E. AU - Corrada-Bravo, H. AU - Ladd-Acosta, C. AU - Feinberg, A. P. AU - Hansen, K. D. PY - 2014 DA - 2014// TI - Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays JO - Bioinformatics. VL - 30 UR - https://doi.org/10.1093/bioinformatics/btu049 DO - 10.1093/bioinformatics/btu049 ID - Aryee2014 ER - TY - JOUR AU - Fortin, J. -. P. AU - Triche, T. J. AU - Hansen, K. D. PY - 2016 DA - 2016// TI - Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi JO - Bioinformatics VL - 33 UR - https://doi.org/10.1093/bioinformatics/btw691 DO - 10.1093/bioinformatics/btw691 ID - Fortin2016 ER - TY - JOUR AU - Horvath, S. AU - Raj, K. PY - 2018 DA - 2018// TI - DNA methylation-based biomarkers and the epigenetic clock theory of ageing JO - Nat Rev Genet VL - 19 UR - https://doi.org/10.1038/s41576-018-0004-3 DO - 10.1038/s41576-018-0004-3 ID - Horvath2018 ER - TY - JOUR AU - McEwen, L. M. AU - Jones, M. J. AU - Lin, D. T. S. AU - Edgar, R. D. AU - Husquin, L. T. AU - MacIsaac, J. L. PY - 2018 DA - 2018// TI - Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array JO - Clin Epigenetics VL - 10 UR - https://doi.org/10.1186/s13148-018-0556-2 DO - 10.1186/s13148-018-0556-2 ID - McEwen2018 ER - TY - JOUR AU - Sylvestre, M. -. P. AU - McCusker, J. AU - Cole, M. AU - Regeasse, A. AU - Belzile, E. AU - Abrahamowicz, M. PY - 2006 DA - 2006// TI - Classification of patterns of delirium severity scores over time in an elderly population JO - Int Psychogeriatr VL - 18 UR - https://doi.org/10.1017/S1041610206003334 DO - 10.1017/S1041610206003334 ID - Sylvestre2006 ER - TY - JOUR AU - Leffondré, K. AU - Abrahamowicz, M. AU - Regeasse, A. AU - Hawker, G. A. AU - Badley, E. M. AU - McCusker, J. PY - 2004 DA - 2004// TI - Statistical measures were proposed for identifying longitudinal patterns of change in quantitative health indicators JO - J Clin Epidemiol VL - 57 UR - https://doi.org/10.1016/j.jclinepi.2004.02.012 DO - 10.1016/j.jclinepi.2004.02.012 ID - Leffondré2004 ER - TY - JOUR AU - Marceau, P. AU - Biron, S. AU - Marceau, S. AU - Hould, F. -. S. AU - Lebel, S. AU - Lescelleur, O. PY - 2015 DA - 2015// TI - Long-term metabolic outcomes 5 to 20 years after biliopancreatic diversion JO - Obes Surg VL - 25 UR - https://doi.org/10.1007/s11695-015-1599-5 DO - 10.1007/s11695-015-1599-5 ID - Marceau2015 ER - TY - BOOK PY - 2018 DA - 2018// TI - R: a language and environment for statistical computing PB - R Foundation for Statistical Computing CY - Vienna ID - ref46 ER - TY - JOUR AU - Faul, F. AU - Erdfelder, E. AU - Lang, A. -. G. AU - Buchner, A. PY - 2007 DA - 2007// TI - G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences JO - Behav Res Methods VL - 39 UR - https://doi.org/10.3758/BF03193146 DO - 10.3758/BF03193146 ID - Faul2007 ER -