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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Perturbations in imprinted methylation from assisted reproductive technologies but not advanced maternal age in mouse preimplantation embryos

Fig. 4

ARTs generated a loss of imprinted methylation maintenance at the (aSnrpn, (bKcnq1ot1, and (cH19 ICRs in blastocysts from young mothers. Diamonds represent the mean methylation levels of maternal (red) or paternal (blue) alleles for Snrpn, Kcnq1ot1, and H19 ICRs in individual embryos (n = 9–17 blastocysts; n = 3–4 females per treatment group). SO, superovulation; EC, embryo culture. Letters (a, b, c), a statistically significant difference between groups (Additional file 1: Table S1)

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