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Table 5 Comparison of GR methylation groups with PAM50 characteristics

From: Region-specific glucocorticoid receptor promoter methylation has both positive and negative prognostic value in patients with estrogen receptor-positive breast cancer

Characteristic C methylated Both C and U unmethylated U methylated, no C methylation χ2 P
N % N % N %
PAM50 subtype
 Luminal A 16 44.4 48 51.6 13 36.1 8.602 0.327
 Luminal B 14 38.9 22 23.7 11 30.6
 HER2 5 13.9 15 16.1 10 27.8
 Basal 1 2.8 4 4.3 0 0.0
 Normal 0 0.0 4 4.3 2 5.6
RORS group
 Low 12 33.3 38 40.9 14 38.9 2.667 0.615
 Medium 18 50.0 41 44.1 13 36.1
 High 6 16.7 14 15.1 9 25.0
RORP group
 Low 10 27.8 26 28.0 6 16.7 3.475 0.482
 Medium 17 47.2 52 55.9 21 58.3
 High 9 25.0 15 16.1 9 25.0
RORT group
 Low 8 22.2 26 28.0 7 19.4 1.581 0.812
 Medium 19 52.8 48 51.6 19 52.8
 High 9 25.0 19 20.4 10 27.8
  1. PAM50 data was available for 165 samples