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Table 5 Comparison of GR methylation groups with PAM50 characteristics

From: Region-specific glucocorticoid receptor promoter methylation has both positive and negative prognostic value in patients with estrogen receptor-positive breast cancer

Characteristic

C methylated

Both C and U unmethylated

U methylated, no C methylation

χ2

P

N

%

N

%

N

%

PAM50 subtype

 Luminal A

16

44.4

48

51.6

13

36.1

8.602

0.327

 Luminal B

14

38.9

22

23.7

11

30.6

 HER2

5

13.9

15

16.1

10

27.8

 Basal

1

2.8

4

4.3

0

0.0

 Normal

0

0.0

4

4.3

2

5.6

RORS group

 Low

12

33.3

38

40.9

14

38.9

2.667

0.615

 Medium

18

50.0

41

44.1

13

36.1

 High

6

16.7

14

15.1

9

25.0

RORP group

 Low

10

27.8

26

28.0

6

16.7

3.475

0.482

 Medium

17

47.2

52

55.9

21

58.3

 High

9

25.0

15

16.1

9

25.0

RORT group

 Low

8

22.2

26

28.0

7

19.4

1.581

0.812

 Medium

19

52.8

48

51.6

19

52.8

 High

9

25.0

19

20.4

10

27.8

  1. PAM50 data was available for 165 samples