|
Gene
|
DNA methylation
|
GENE EXPRESSION
|
|---|
|
CpG annotation
|
Gene annotation
|
FDR
|
β fold change
|
Probe ID
|
p value
|
Log fold change
|
|---|
|
RASGRP1
|
chr15:38,781,997
|
3′UTR
|
0.049
|
0.041
|
2,760,239
|
0.002
|
− 0.285
|
|
BCL11A
|
chr2:60,766,554
|
Body
|
0.043
|
0.069
|
6,580,450
|
0.005
|
−0.280
|
|
3,170,440
|
0.014
|
−0.232
|
|
ST13P4
|
chr13:50,745,306
|
TSS1500
|
0.045
|
0.046
|
4,050,195
|
0.007
|
−0.236
|
|
C7orf50
|
chr7:1,053,726
|
Body
|
0.043
|
0.112
|
5,810,671
|
0.008
|
0.206
|
|
WWP1
|
chr8:87,427,271
|
Body
|
0.045
|
0.041
|
1,980,201
|
0.009
|
−0.204
|
|
UBE3C
|
chr7:156,951,457
|
Body
|
0.046
|
0.090
|
1,690,709
|
0.010
|
−0.156
|
|
RB1CC1
|
chr8:53,566,460
|
Body
|
0.045
|
0.086
|
3,890,092
|
0.012
|
−0.224
|
|
PUM1
|
chr1:31,486,063
|
Body
|
< 0.001
|
0.066
|
3,870,543
|
0.022
|
−0.162
|
|
SMC3
|
chr10:112,331,306
|
Body
|
0.047
|
0.059
|
2,970,292
|
0.024
|
−0.187
|
|
RPS24
|
chr10:79,793,501
|
TSS200
|
0.046
|
− 0.014
|
830,066
|
0.025
|
−0.593
|
|
RPS6KB1
|
chr17:57,970,021
|
TSS1500
|
0.045
|
− 0.027
|
1,940,576
|
0.026
|
−0.194
|
|
KMT2E
|
chr7:104,696,669
|
Body
|
0.045
|
0.050
|
3,120,050
|
0.033
|
0.249
|
|
FAM217B
|
chr20:58,520,201
|
3′UTR
|
0.044
|
0.024
|
770,221
|
0.039
|
0.228
|
|
NIN
|
chr14:51,295,867
|
5′UTR
|
0.043
|
0.078
|
5,310,717
|
0.043
|
−0.150
|
|
HNRNPM
|
chr19:8,513,923
|
Body
|
0.043
|
0.073
|
2,360,669
|
0.045
|
−0.150
|
- Differentially methylated positions (DMPs) associated with the emergence of dimensional psychopathology in youths that had gene expression in peripheral venous blood identified by a HumanHT-12 v4.0 Expression BeadChip (Illumina). Probe location and gene annotation were taken from Illumina reference files. Annotation was performed according to hg19. Wave 0 (baseline) was used as the reference for both the DNA methylation and gene expression analyses. Probe ID unique identifier from the gene expression Illumina database. TSS200 0–200 bases upstream of the transcriptional start site (TSS). TSS1500 200–1500 bases upstream of the TSS. Official full names of the genes mentioned in the text: BCL11A B cell CLL/lymphoma 11A, KMT2E lysine methyltransferase 2E, RB1CC1 RB1 inducible coiled-coil 1, FAM217B family with sequence similarity 217 member B
