Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths

Table 2 The 20 most differentially methylated positions (DMPs) associated with the emergence of dimensional psychopathology

CpG ID	β fold change	Adjusted p value	Chromosome	Position (bp)	Gene annotation
cg11166600	0.1002	0.0037	chr3	143,695,141	C3orf58 (body)
cg15427886	0.0896	0.0039	chr8	55,379,663	–
cg14116799	− 0.0764	0.0092	chr10	43,800,154	–
cg03213396	0.0699	0.0107	chr19	53,760,449	VN1R2 (TSS1500)
cg25024195	0.0925	0.0253	chr17	46,144,968	–
cg03638479	− 0.0667	0.0253	chr3	52,009,768	ABHD14B (TSS1500); ABHD14A (body)
cg14525247	0.0630	0.0253	chr9	131,154,899	MIR219–2 (body)
cg25275750	0.0562	0.0410	chr13	75,918,697	TBC1D4 (body)
cg10544031	− 0.0261	0.0410	chr2	223,164,635	PAX3 (TSS1500, 5′UTR); CCDC140 (TSS1500)
cg22871870	0.0525	0.0415	chr15	77,348,431	TSPAN3 (body)
cg20664238	0.0193	0.0415	chr15	88,798,877	NTRK3 (body)
cg05673214	0.0498	0.0415	chr16	743,476	FBXL16 (3′UTR)
cg01215511	0.0681	0.0414	chr16	2,975,552	FLYWCH1 (5′UTR)
cg09288320	0.0770	0.0415	chr2	210,994,670	C2orf67 (Body)
cg00137855	0.0612	0.0415	chr5	74,163,723	FAM169A (TSS1500)
cg19377326	0.0657	0.0416	chr1	31,486,063	PUM1 (Body)
cg03729042	0.0444	0.0416	chr1	183,560,923	NCF2 (TSS1500)
cg00589617	0.0647	0.0416	chr1	230,415,343	GALNT2 (3’UTR)
cg24250902	0.0682	0.0416	chr1	230,415,547	GALNT2 (3’UTR)
cg03754250	− 0.0394	0.0416	chr10	31,320,338	ZNF438 (5’UTR, Body)

Wave 0 was used as the reference. Annotation was performed according to hg19, and the probe location and gene annotation were taken from Illumina reference files. CpG ID unique identifier from the Illumina CG database. Adjusted p value: false discovery rate (FDR) procedure using the Benjamini–Hochberg method (FDR < 0.05). TSS1500 200–1500 bases upstream of the transcriptional start site (TSS)

ISSN: 1868-7083