Table 2 Early changes in methylation patterns and associated clinical variables

CpG methylation Index

0 (0–58.4)

0.005

74.7 (0–85.3)

0.273

0.025

77.9 (70.8–86.7)

Additional CpG methylation Index^d

0.8 (0–21.0)

0.155

27.0 (4.3–45.1)

0.163

0.074

20.0 (13.8–20.0)

Non–CpG methylation Index^e

1.3 (0–9.5)

0.388

0 (0–0)

0.332

0.093

0 (0–2.2)

Residual pVL (RNA copies/mL)

1.4 (0–3.6)

0.737

3.4 (0–7.1)

0.305

0.176

0.4 (0–2.9)

Proviral load (DNA copies/million CD4⁺ T cells)

14146 (517–29277)

0.526

3638 (228–10216)

0.260

0.005

9780 (4 057–13716)

Naive CD4⁺ T cells (%)

25.2 (20.6–52.6)

0.944

29.1 (18.3–49.1)

0.888

0.114

39.4 (11.2–45.4)

Memory CD4⁺ T cells (%)

74.8 (47.4–79.4)

0.944

70.9 (50.9–81.7)

0.888

0.114

60.6 (54.6–88.8)

 T_SCM (%)

5.6 (3.0–6.9)

0.049

4.2 (2.9–7.1)

0.035

0.508

9.4 (5.7–15.9)

 T_CM (%)

23.2 (15.3–31.2)

0.673

21.7 (12.7–33.0)

0.439

0.169

23.8 (19.5–40.9)

 T_EM (%)

12.5 (2.1–20.4)

0.398

10.1 (3.2–12.5)

0.205

0.333

6.3 (4.8–9.3)

 T_TM (%)

15.0 (11.3–25.4)

0.091

13.8 (11.4–31.5)

0.049

0.799

8.3 (4.5–16.6)

 T_NEW (%)

1.1 (0.6–1.5)

0.003

2.5 (1.6–3.6)

0.526

0.005

2.0 (1.5–3.9)

T_TE (%)

2.3 (0.3–11.1)

0.181

5.0 (1.2–9.8)

0.944

0.285

4.8 (2.7–7.8)