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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Longitudinal variation in human immunodeficiency virus long terminal repeat methylation in individuals on suppressive antiretroviral therapy

Fig. 4

Changes in CpG Methylation Index, proviral load and residual plasma viral load along study follow-up. a The CpG Methylation Index was calculated as the average proportion of methylated variants considering the nine canonical HXB2 CpG sites analyzed, for each person and time point; all participants are included. b Participants were divided according to methylation patterns along time into two groups: constant methylation and methylation increase. CpG Methylation Index variations are shown for each group. c Proviral load variation along time for the constant methylation and methylation increase groups is shown. d Residual plasma viral load along time for the constant methylation and methylation increase groups is shown. In all cases, boxes represent 25–75% quartiles, whiskers 10–90% deciles, and horizontal lines within boxes represent medians

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