Fig. 4
Changes in CpG Methylation Index, proviral load and residual plasma viral load along study follow-up. a The CpG Methylation Index was calculated as the average proportion of methylated variants considering the nine canonical HXB2 CpG sites analyzed, for each person and time point; all participants are included. b Participants were divided according to methylation patterns along time into two groups: constant methylation and methylation increase. CpG Methylation Index variations are shown for each group. c Proviral load variation along time for the constant methylation and methylation increase groups is shown. d Residual plasma viral load along time for the constant methylation and methylation increase groups is shown. In all cases, boxes represent 25–75% quartiles, whiskers 10–90% deciles, and horizontal lines within boxes represent medians