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Table 1 Group characteristics and methylation levels

From: Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom

 

Control group

MSD patients

Male

Female

Male

Female

Mean

Standard deviation

Mean

Standard deviation

Mean

Standard deviation

Mean

Standard deviation

Age (years)

46.06

14.44

53.32

8.72

51.67

9.38

55.14

10.11

Body mass index

25.02

3.38

24.20

3.96

26.63

3.75

27.02

5.26

SF-36 physical sum score

55.11

3.57

53.86

5.95

30.09

7.75

28.62

7.83

VAS (0–10)

1.17

2.27

1.82

2.62

7.12

1.50

7.00

1.55

CpG -734 methylation

0.97

0.07

0.96

0.09

0.98

0.04

0.98

0.05

CpG -720 methylation

0.91

0.03

0.92

0.03

0.91

0.04

0.91

0.03

CpG -628 methylation

0.50

0.06

0.54

0.06

0.51

0.07

0.55

0.06

CpG -480 methylation

0.02

0.07

0.01

0.03

0.03

0.10

0.02

0.06

CpG -452 methylation

0.05

0.07

0.09

0.08

0.05

0.05

0.09

0.11

CpG -429 methylation

0.52

0.11

0.55

0.08

0.51

0.09

0.55

0.09

CpG -412 methylation

0.29

0.13

0.28

0.07

0.28

0.13

0.28

0.09

Mean methylation

0.47

0.03

0.48

0.03

0.47

0.04

0.48

0.04

  1. Group characteristics, psychometric scores, pain measured on visual analog scale (VAS) and methylation levels of individual CpGs and mean methylation (range 0–1.0, i.e., no to complete methylation) of MSD patients and controls split according to gender
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Clinical Epigenetics

ISSN: 1868-7083

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