Skip to main content

Advertisement

Table 1 Characteristics of the samples utilized in the study

From: Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease

  Controls Cases
Study and sample type No of subjects (male/female) Age range (years) No of subjects (male/female) Age range (years)
Finnish cohort (n = 97)
 Peripheral blood (n = 93)
  ADDa MZ twin pairs 12/9 67–86 12/9 67–86
  ADD DZ twin pairs 6/6 70–72 6/6 70–72
  Unrelated individuals 1/8 61–77 9/9 70–86
 Peripheral blood mononuclear cells (n = 4)
  MZ twin pairs discordant for episodic memory 2/0 76 2/0 76
Swedish cohort (n = 298)
 Peripheral blood (n = 298)
  ADD MZ twin pairs 5/5 62–83 5/5 63-83
  ADD DZ twin pairs 11/8 63–84 11/8 63–84
  Incidentb ADD MZ twin pairs 15/23 62–85 15/23 62–85
  Incident ADD DZ twin pairs 33/49 53–88 33/49 53–88
NIH NeuroBioBank (n = 12)
 Anterior hippocampus with entorhinal cortex (n = 12)
  Unrelated individuals 4/2 56–89   4/2 57–90
Total (n = 407) 89/110 53–90   97/111 53–90
  1. aAlzheimer’s disease-discordant
  2. bSample collected 0.5–18.5 years before disease onset