Duration of breastfeeding is associated with leptin ( LEP ) DNA methylation profiles and BMI in 10-year-old children

Table 4 Statistically significant differentially methylated regions (DMRs) (Sidak P value < 0.05) for total breastfeeding duration

Age	Location	No. of probes	Slk P value	Sidak P value	Ref gene name and genomic feature		CpG feature
10	chr10:104535854-104535920	2	4.62E−07	0.005	WBP1L	TSS200; body; 5′UTR;1stExon	NA
10	chr19:54567060-54567128	3	3.74E−07	0.004	VSTM1	5′UTR;1stExon; body	NA
18	chr22:37678728-37678791	2	2.49E−07	0.002	CYTH4	Body	NA

Both Slk = uncorrected Stouffer-Liptak-Kechris P values, and Sidak P values corrected for multiple testing are reported. Here, 5′UTR = 5 prime untranslated region; TSS200 = 0–200 bases upstream from the transcription start sites; TSS1500 = 200–1500 bases upstream from the transcriptional start site; body = gene body