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Fig. 4. | Clinical Epigenetics

Fig. 4.

From: DNA methylome-wide alterations associated with estrogen receptor-dependent effects of bisphenols in breast cancer

Fig. 4.

Cell migration assay of MCF-7 cells treated with BPA, BPF, and BPS ± ERI. Migration (scratch assay) of MCF-7 cells is shown following treatment with exposure and functional doses of BPA (a), BPF (b), and BPS (c) ± ERI. Data are presented as mean distance traveled (arbitrary unit) ± standard error of the mean (SEM) at time points 0, 2, 4, 6, 8, 10, 12, and 24 h in at least three independent trials. Comparisons were performed at every time point between each treatment condition and control using two-way analysis of variance (ANOVA) followed by Dunnett post hoc test (*p < 0.05 and **p < 0.001), and between the same treatment condition in the presence and absence of ERI using two-way ANOVA followed by Tukey’s HSD (honestly significant difference) post hoc test (#p < 0.05)

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