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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Deficiency and haploinsufficiency of histone macroH2A1.1 in mice recapitulate hematopoietic defects of human myelodysplastic syndrome

Fig. 4

RNA-Seq and bio-informatic analyses on multipotent progenitor cells (CD150CD48+ LSK) isolated from bone marrow and using flow cytometry. a KEGG pathways significantly represented by the differentially expressed genes. Enrichment-log (p values) is reported on the x-axis. The dashed red line marks the significant enrichment threshold (p value = 0.05). b Mouse KEGG map (mmu03010) of the Ribosome pathway. c Top 20 most enriched Gene Ontology biological processes. The blue line marks the significance enrichment threshold (p value = 0.05), and text within a bar refers to the number of significantly expressed genes belonging to a process and the overall enrichment score (into brackets)

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