Skip to main content

Table 1 IC50 values of chidamide and MI-3 as single agent in AML cells

From: Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair

  

Chidamide

 

MI-3

 
  

IC50(μM)

95%CI

IC50(μM)

95%CI

 

24 h

8.240

4.868–13.950

53.54

33.920–84.510

MOLM-13

48 h

6.578

4.782–9.050

34.69

23.240–51.790

 

72 h

1.180

0.332–4.192

13.11

7.502–22.920

 

24 h

4.623

3.822–5.593

53.72

29.770–96.910

MV4-11

48 h

2.630

1.438–4.810

44.90

39.250–51.370

 

72 h

2.379

1.274–4.443

15.01

9.520–23.680