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Table 1 IC50 values of chidamide and MI-3 as single agent in AML cells

From: Co-inhibition of HDAC and MLL-menin interaction targets MLL-rearranged acute myeloid leukemia cells via disruption of DNA damage checkpoint and DNA repair

   Chidamide   MI-3  
   IC50(μM) 95%CI IC50(μM) 95%CI
  24 h 8.240 4.868–13.950 53.54 33.920–84.510
MOLM-13 48 h 6.578 4.782–9.050 34.69 23.240–51.790
  72 h 1.180 0.332–4.192 13.11 7.502–22.920
  24 h 4.623 3.822–5.593 53.72 29.770–96.910
MV4-11 48 h 2.630 1.438–4.810 44.90 39.250–51.370
  72 h 2.379 1.274–4.443 15.01 9.520–23.680