TY - JOUR AU - Kuykendall, A. AU - Duployez, N. AU - Boissel, N. AU - Lancet, J. E. AU - Welch, J. S. PY - 2018 DA - 2018// TI - Acute myeloid leukemia: the good, the bad, and the ugly. American Society of Clinical Oncology educational book JO - Am Soc Clin Oncol VL - 38 UR - https://doi.org/10.1200/EDBK_199519 DO - 10.1200/EDBK_199519 ID - Kuykendall2018 ER - TY - JOUR AU - Kim, H. J. AU - Cho, H. I. AU - Kim, E. C. AU - Ko, E. K. AU - See, C. J. AU - Park, S. Y. PY - 2002 DA - 2002// TI - A study on 289 consecutive Korean patients with acute leukaemias revealed fluorescence in situ hybridization detects the MLL translocation without cytogenetic evidence both initially and during follow-up JO - Br J Haematol VL - 119 UR - https://doi.org/10.1046/j.1365-2141.2002.03937.x DO - 10.1046/j.1365-2141.2002.03937.x ID - Kim2002 ER - TY - JOUR AU - Grimwade, D. AU - Hills, R. K. AU - Moorman, A. V. AU - Walker, H. AU - Chatters, S. AU - Goldstone, A. H. PY - 2010 DA - 2010// TI - Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials JO - Blood. VL - 116 UR - https://doi.org/10.1182/blood-2009-11-254441 DO - 10.1182/blood-2009-11-254441 ID - Grimwade2010 ER - TY - JOUR AU - BV, B. AU - Raimondi, S. C. AU - Harbott, J. AU - Zimmermann, M. AU - Alonzo, T. A. AU - Auvrignon, A. PY - 2009 DA - 2009// TI - Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study JO - Blood. VL - 114 UR - https://doi.org/10.1182/blood-2009-04-215152 DO - 10.1182/blood-2009-04-215152 ID - BV2009 ER - TY - JOUR AU - Marneth, A. E. AU - Prange, K. H. M. AU - Hinai, A. S. A. AU - Bergevoet, S. M. AU - Tesi, N. AU - Janssen-Megens, E. M. PY - 2018 DA - 2018// TI - C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation JO - Leukemia. VL - 32 UR - https://doi.org/10.1038/leu.2017.280 DO - 10.1038/leu.2017.280 ID - Marneth2018 ER - TY - JOUR AU - Muntean, A. G. AU - Hess, J. L. PY - 2012 DA - 2012// TI - The pathogenesis of mixed-lineage leukemia JO - Ann Rev Pathol. VL - 7 UR - https://doi.org/10.1146/annurev-pathol-011811-132434 DO - 10.1146/annurev-pathol-011811-132434 ID - Muntean2012 ER - TY - JOUR AU - Meyer, C. AU - Hofmann, J. AU - Burmeister, T. AU - Gröger, D. AU - Park, T. S. AU - Emerenciano, M. PY - 2013 DA - 2013// TI - The MLL recombinome of acute leukemias in 2013 JO - Leukemia. VL - 27 UR - https://doi.org/10.1038/leu.2013.135 DO - 10.1038/leu.2013.135 ID - Meyer2013 ER - TY - JOUR AU - Zeisig, B. B. AU - Kulasekararaj, A. G. AU - Mufti, G. J. AU - So, C. W. PY - 2012 DA - 2012// TI - SnapShot: acute myeloid leukemia JO - Cancer cell. VL - 22 UR - https://doi.org/10.1016/j.ccr.2012.10.017 DO - 10.1016/j.ccr.2012.10.017 ID - Zeisig2012 ER - TY - JOUR AU - Sheridan, C. PY - 2017 DA - 2017// TI - First new drug approval for AML in 15 years JO - Nature biotechnology. VL - 35 UR - https://doi.org/10.1038/nbt0817-696 DO - 10.1038/nbt0817-696 ID - Sheridan2017 ER - TY - JOUR AU - Zhang, H. AU - Dong, L. AU - Chen, Q. AU - Kong, L. AU - Meng, B. AU - Wang, H. AU - Fu, K. PY - 2017 DA - 2017// TI - Synergistic antitumor effect of histone deacetylase inhibitor and doxorubicin in peripheral T cell lymphoma JO - Leukemia Res. VL - 56 UR - https://doi.org/10.1016/j.leukres.2017.01.025 DO - 10.1016/j.leukres.2017.01.025 ID - Zhang2017 ER - TY - JOUR AU - Ellmeier, W. AU - Seiser, C. PY - 2018 DA - 2018// TI - Histone deacetylase function in CD4(+) T cells JO - Nature reviews. Immunology. VL - 18 UR - https://doi.org/10.1038/s41577-018-0037-z DO - 10.1038/s41577-018-0037-z ID - Ellmeier2018 ER - TY - JOUR AU - Li, Y. AU - Wang, Y. AU - Zhou, Y. AU - Li, J. AU - Chen, K. AU - Zhang, L. PY - 2017 DA - 2017// TI - Cooperative effect of chidamide and chemotherapeutic drugs induce apoptosis by DNA damage accumulation and repair defects in acute myeloid leukemia stem and progenitor cells JO - Clinical epigenetics. VL - 9 UR - https://doi.org/10.1186/s13148-017-0377-8 DO - 10.1186/s13148-017-0377-8 ID - Li2017 ER - TY - JOUR AU - Gao, S. AU - Li, X. AU - Zang, J. AU - Xu, W. AU - Zhang, Y. PY - 2017 DA - 2017// TI - Preclinical and clinical studies of chidamide (CS055/HBI-8000), An orally available subtype-selective HDAC inhibitor for cancer therapy JO - Anti Cancer Agents Med Chem. VL - 17 UR - https://doi.org/10.2174/1871520616666160901150427 DO - 10.2174/1871520616666160901150427 ID - Gao2017 ER - TY - JOUR AU - Shi, P. AU - Zhang, L. AU - Chen, K. AU - Jiang, Z. AU - Deng, M. AU - Zha, J. PY - 2017 DA - 2017// TI - Low-dose decitabine enhances chidamide-induced apoptosis in adult acute lymphoblast leukemia, especially for p16-deleted patients through DNA damage JO - Pharmacogenomics. VL - 18 UR - https://doi.org/10.2217/pgs-2017-0061 DO - 10.2217/pgs-2017-0061 ID - Shi2017 ER - TY - JOUR AU - Blagitko-Dorfs, N. AU - Schlosser, P. AU - Greve, G. AU - Pfeifer, D. AU - Meier, R. AU - Baude, A. PY - 2019 DA - 2019// TI - Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation JO - Leukemia. VL - 33 UR - https://doi.org/10.1038/s41375-018-0293-8 DO - 10.1038/s41375-018-0293-8 ID - Blagitko-Dorfs2019 ER - TY - JOUR AU - Ratner, M. PY - 2014 DA - 2014// TI - Small biotech steers HDAC inhibitor to clinic JO - Nature biotechnology. VL - 32 UR - https://doi.org/10.1038/nbt0914-853 DO - 10.1038/nbt0914-853 ID - Ratner2014 ER - TY - JOUR AU - Yang, H. AU - Maddipoti, S. AU - Quesada, A. AU - Bohannan, Z. AU - Cabrero Calvo, M. AU - Colla, S. PY - 2015 DA - 2015// TI - Analysis of class I and II histone deacetylase gene expression in human leukemia JO - Leuk Lymphoma. VL - 56 UR - https://doi.org/10.3109/10428194.2015.1034705 DO - 10.3109/10428194.2015.1034705 ID - Yang2015 ER - TY - JOUR AU - Chen, J. AU - Santillan, D. A. AU - Koonce, M. AU - Wei, W. AU - Luo, R. AU - Thirman, M. J. PY - 2008 DA - 2008// TI - Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization JO - Cancer research. VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-07-6514 DO - 10.1158/0008-5472.CAN-07-6514 ID - Chen2008 ER - TY - JOUR AU - Li, X. AU - Yan, X. AU - Guo, W. AU - Huang, X. AU - Huang, J. AU - Yu, M. PY - 2017 DA - 2017// TI - Chidamide in FLT3-ITD positive acute myeloid leukemia and the synergistic effect in combination with cytarabine JO - Biomed Pharmacother. VL - 90 UR - https://doi.org/10.1016/j.biopha.2017.04.037 DO - 10.1016/j.biopha.2017.04.037 ID - Li2017 ER - TY - JOUR AU - Karnik, S. K. AU - Hughes, C. M. AU - Gu, X. AU - Rozenblatt-Rosen, O. AU - McLean, G. W. AU - Xiong, Y. PY - 2005 DA - 2005// TI - Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c JO - Proc Natl Acad Sci U S A. VL - 102 UR - https://doi.org/10.1073/pnas.0503484102 DO - 10.1073/pnas.0503484102 ID - Karnik2005 ER - TY - JOUR AU - Gallo, A. AU - Agnese, S. AU - Esposito, I. AU - Galgani, M. AU - Avvedimento, V. E. PY - 2010 DA - 2010// TI - Menin stimulates homology-directed DNA repair JO - FEBS Letters. VL - 584 UR - https://doi.org/10.1016/j.febslet.2010.10.032 DO - 10.1016/j.febslet.2010.10.032 ID - Gallo2010 ER - TY - JOUR AU - Borkin, D. AU - Pollock, J. AU - Kempinska, K. AU - Purohit, T. AU - Li, X. AU - Wen, B. PY - 2016 DA - 2016// TI - Property focused structure-based optimization of small molecule inhibitors of the protein-protein interaction between menin and mixed lineage leukemia (MLL) JO - J Med Chem. VL - 59 UR - https://doi.org/10.1021/acs.jmedchem.5b01305 DO - 10.1021/acs.jmedchem.5b01305 ID - Borkin2016 ER - TY - JOUR AU - Borkin, D. AU - Klossowski, S. AU - Pollock, J. AU - Miao, H. AU - Linhares, B. M. AU - Kempinska, K. PY - 2018 DA - 2018// TI - Complexity of blocking bivalent protein-protein interactions: development of a highly potent inhibitor of the menin-mixed-lineage leukemia interaction JO - J Med Chem. VL - 61 UR - https://doi.org/10.1021/acs.jmedchem.8b00071 DO - 10.1021/acs.jmedchem.8b00071 ID - Borkin2018 ER - TY - JOUR AU - Wang, R. AU - Zhang, S. AU - Chen, X. AU - Li, N. AU - Li, J. AU - Jia, R. PY - 2018 DA - 2018// TI - CircNT5E acts as a sponge of miR-422a to promote glioblastoma tumorigenesis JO - Cancer Res. VL - 78 UR - https://doi.org/10.1158/0008-5472.CAN-18-0532 DO - 10.1158/0008-5472.CAN-18-0532 ID - Wang2018 ER - TY - JOUR AU - Jarman, P. J. AU - Noakes, F. AU - Fairbanks, S. AU - Smitten, K. AU - Griffiths, I. K. AU - Saeed, H. K. PY - 2019 DA - 2019// TI - Exploring the cytotoxicity, uptake, cellular response, and proteomics of mono- and dinuclear DNA light-switch complexes JO - J Am Chem Soc. VL - 141 UR - https://doi.org/10.1021/jacs.8b09999 DO - 10.1021/jacs.8b09999 ID - Jarman2019 ER - TY - JOUR AU - Garrido Castro, P. AU - Roon, E. H. J. AU - Pinhanços, S. S. AU - Trentin, L. AU - Schneider, P. AU - Kerstjens, M. PY - 2018 DA - 2018// TI - The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis JO - Leukemia VL - 32 UR - https://doi.org/10.1038/leu.2017.216 DO - 10.1038/leu.2017.216 ID - Garrido Castro2018 ER - TY - JOUR AU - Shen, Y. AU - Wei, W. AU - Zhou, D. X. PY - 2015 DA - 2015// TI - Histone acetylation enzymes coordinate metabolism and gene expression JO - Trends Plant Sci. VL - 20 UR - https://doi.org/10.1016/j.tplants.2015.07.005 DO - 10.1016/j.tplants.2015.07.005 ID - Shen2015 ER - TY - JOUR AU - Ashkar, S. AU - Schwaller, J. AU - Pieters, T. AU - Goossens, S. AU - Demeulemeester, J. AU - Christ, F. PY - 2018 DA - 2018// TI - LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis JO - Blood. VL - 131 ID - Ashkar2018 ER - TY - JOUR AU - Yokoyama, A. PY - 2015 DA - 2015// TI - Molecular mechanisms of MLL-associated leukemia JO - Int J Hematol. VL - 101 UR - https://doi.org/10.1007/s12185-015-1774-4 DO - 10.1007/s12185-015-1774-4 ID - Yokoyama2015 ER - TY - JOUR AU - Xia, Y. AU - Shen, S. AU - Verma, I. M. PY - 2014 DA - 2014// TI - NF-kappaB, an active player in human cancers JO - Cancer Immunol Res. VL - 2 UR - https://doi.org/10.1158/2326-6066.CIR-14-0112 DO - 10.1158/2326-6066.CIR-14-0112 ID - Xia2014 ER - TY - JOUR AU - Liang, K. AU - Volk, A. G. AU - Haug, J. S. AU - Marshall, S. A. AU - Woodfin, A. R. AU - Bartom, E. T. PY - 2017 DA - 2017// TI - Therapeutic targeting of MLL degradation pathways in MLL-rearranged leukemia JO - Cell. VL - 168 UR - https://doi.org/10.1016/j.cell.2016.12.011 DO - 10.1016/j.cell.2016.12.011 ID - Liang2017 ER - TY - JOUR AU - Yasuda, S. AU - Yasuda, T. AU - Liu, M. Y. AU - Shetty, S. AU - Idell, S. AU - Boggaram, V. PY - 2011 DA - 2011// TI - Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3 JO - Toxicol Appl Pharmacol. VL - 251 UR - https://doi.org/10.1016/j.taap.2010.12.006 DO - 10.1016/j.taap.2010.12.006 ID - Yasuda2011 ER - TY - JOUR AU - Yasuda, S. AU - Idell, S. AU - Liu, M. C. PY - 2007 DA - 2007// TI - Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: identification of SULT1A3 as the enzyme responsible JO - Biochem J. VL - 401 UR - https://doi.org/10.1042/BJ20060536 DO - 10.1042/BJ20060536 ID - Yasuda2007 ER - TY - JOUR AU - King, H. O. AU - Brend, T. AU - Payne, H. L. AU - Wright, A. AU - Ward, T. A. AU - Patel, K. PY - 2017 DA - 2017// TI - RAD51 Is a Selective DNA repair target to radiosensitize glioma stem cells JO - Stem Cell Rep. VL - 8 UR - https://doi.org/10.1016/j.stemcr.2016.12.005 DO - 10.1016/j.stemcr.2016.12.005 ID - King2017 ER - TY - JOUR AU - Tsukuda, T. AU - Fleming, A. B. AU - Nickoloff, J. A. AU - Osley, M. A. PY - 2005 DA - 2005// TI - Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae JO - Nature. VL - 438 UR - https://doi.org/10.1038/nature04148 DO - 10.1038/nature04148 ID - Tsukuda2005 ER - TY - JOUR AU - Kühn, M. W. AU - Armstrong, S. A. PY - 2015 DA - 2015// TI - Designed to kill: novel menin-MLL inhibitors target MLL-rearranged leukemia JO - Cancer Cell. VL - 27 UR - https://doi.org/10.1016/j.ccell.2015.03.012 DO - 10.1016/j.ccell.2015.03.012 ID - Kühn2015 ER - TY - JOUR AU - Grembecka, J. AU - He, S. AU - Shi, A. AU - Purohit, T. AU - Muntean, A. G. AU - Sorenson, R. J. PY - 2012 DA - 2012// TI - Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia JO - Nat Chem Biol. VL - 8 UR - https://doi.org/10.1038/nchembio.773 DO - 10.1038/nchembio.773 ID - Grembecka2012 ER - TY - JOUR AU - Borkin, D. AU - He, S. AU - Miao, H. AU - Kempinska, K. AU - Pollock, J. AU - Chase, J. PY - 2015 DA - 2015// TI - Pharmacologic inhibition of the menin-MLL interaction blocks progression of MLL leukemia in vivo JO - Cancer Cell. VL - 27 UR - https://doi.org/10.1016/j.ccell.2015.02.016 DO - 10.1016/j.ccell.2015.02.016 ID - Borkin2015 ER - TY - JOUR AU - Chen, Y. AU - Jones, K. L. AU - Anastassiadis, K. AU - Kranz, A. AU - Stewart, A. F. AU - Grembecka, J. PY - 2019 DA - 2019// TI - Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia JO - Exp Hematol. VL - 69 UR - https://doi.org/10.1016/j.exphem.2018.10.001 DO - 10.1016/j.exphem.2018.10.001 ID - Chen2019 ER - TY - JOUR AU - Xu, S. AU - Aguilar, A. AU - Xu, T. AU - Zheng, K. AU - Huang, L. AU - Stuckey, J. PY - 2018 DA - 2018// TI - Design of the first-in-class, highly potent irreversible inhibitor targeting the menin-MLL protein-protein interaction JO - Angewandte Chemie VL - 57 UR - https://doi.org/10.1002/anie.201711828 DO - 10.1002/anie.201711828 ID - Xu2018 ER - TY - JOUR AU - Eckschlager, T. 1. AU - Plch, J. 2. AU - Stiborova, M. 3. AU - Hrabeta, J. PY - 2017 DA - 2017// TI - Histone deacetylase inhibitors as anticancer drugs JO - Int J Mol Sci. VL - 18 UR - https://doi.org/10.3390/ijms18071414 DO - 10.3390/ijms18071414 ID - Eckschlager2017 ER - TY - JOUR AU - Souza, C. AU - Chatterji, B. P. PY - 2015 DA - 2015// TI - HDAC inhibitors as novel anti-cancer therapeutics JO - Recent Pat Anti-Cancer Drug Discov. VL - 10 UR - https://doi.org/10.2174/1574892810666150317144511 DO - 10.2174/1574892810666150317144511 ID - Souza2015 ER - TY - JOUR AU - Hull, E. E. AU - Montgomery, M. R. AU - Leyva, K. J. PY - 2016 DA - 2016// TI - HDAC Inhibitors as epigenetic regulators of the immune system: impacts on cancer therapy and inflammatory diseases JO - BioMed Res Int. VL - 2016 UR - https://doi.org/10.1155/2016/8797206 DO - 10.1155/2016/8797206 ID - Hull2016 ER - TY - JOUR AU - Thomas, X. PY - 2017 DA - 2017// TI - Randomized phase II study of clofarabine-based consolidation for younger adults with acute myeloid leukemia in first remission JO - J Clin Oncol. VL - 35 UR - https://doi.org/10.1200/JCO.2016.70.4551 DO - 10.1200/JCO.2016.70.4551 ID - Thomas2017 ER - TY - JOUR AU - Zhou, L. AU - Chen, S. AU - Zhang, Y. AU - Kmieciak, M. AU - Leng, Y. AU - Li, L. AU - Lin, H. AU - Rizzo, K. A. AU - Dumur, C. I. AU - Ferreira-Gonzalez, A. AU - Rahmani, M. AU - Povirk, L. AU - Chalasani, S. AU - Berger, A. J. AU - Dai, Y. AU - Grant, S. PY - 2016 DA - 2016// TI - The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR JO - Blood VL - 127 UR - https://doi.org/10.1182/blood-2015-06-653717 DO - 10.1182/blood-2015-06-653717 ID - Zhou2016 ER - TY - JOUR AU - Burbury, K. L. PY - 2016 DA - 2016// TI - MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi) JO - Ann Hematol. VL - 127 ID - Burbury2016 ER - TY - JOUR AU - Smith, E. AU - Lin, C. AU - Shilatifard, A. PY - 2011 DA - 2011// TI - The super elongation complex (SEC) and MLL in development and disease JO - Genes Dev. VL - 25 UR - https://doi.org/10.1101/gad.2015411 DO - 10.1101/gad.2015411 ID - Smith2011 ER - TY - JOUR AU - Minzel, W. AU - Venkatachalam, A. AU - Fink, A. AU - Hung, E. AU - Brachya, G. AU - Burstain, I. PY - 2018 DA - 2018// TI - Small molecules co-targeting CKIalpha and the transcriptional kinases CDK7/9 control AML in preclinical models JO - Cell. VL - 175 UR - https://doi.org/10.1016/j.cell.2018.07.045 DO - 10.1016/j.cell.2018.07.045 ID - Minzel2018 ER - TY - JOUR AU - Kim, J. H. AU - Baddoo, M. C. AU - Park, E. Y. AU - Stone, J. K. AU - Park, H. AU - Butler, T. W. PY - 2016 DA - 2016// TI - SON and its alternatively spliced isoforms control MLL complex-mediated H3K4me3 and transcription of leukemia-associated genes JO - Mol Cell. VL - 61 UR - https://doi.org/10.1016/j.molcel.2016.02.024 DO - 10.1016/j.molcel.2016.02.024 ID - Kim2016 ER - TY - JOUR AU - He, S. AU - Malik, B. AU - Borkin, D. AU - Miao, H. AU - Shukla, S. AU - Kempinska, K. PY - 2016 DA - 2016// TI - Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner JO - Leukemia. VL - 30 UR - https://doi.org/10.1038/leu.2015.144 DO - 10.1038/leu.2015.144 ID - He2016 ER - TY - JOUR AU - Dafflon, C. AU - Craig, V. J. AU - Méreau, H. AU - Gräsel, J. AU - Schacher Engstler, B. AU - Hoffman, G. PY - 2017 DA - 2017// TI - Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia JO - Leukemia. VL - 31 UR - https://doi.org/10.1038/leu.2016.327 DO - 10.1038/leu.2016.327 ID - Dafflon2017 ER - TY - JOUR AU - Guha, M. PY - 2015 DA - 2015// TI - HDAC inhibitors still need a home run, despite recent approval JO - Nat Rev Drug Discov. VL - 14 UR - https://doi.org/10.1038/nrd4583 DO - 10.1038/nrd4583 ID - Guha2015 ER - TY - JOUR AU - Sun, Y. AU - Liu, W. Z. AU - Liu, T. AU - Feng, X. AU - Yang, N. AU - Zhou, H. F. PY - 2015 DA - 2015// TI - Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis JO - J Recept Signal Transduct Res. VL - 35 UR - https://doi.org/10.3109/10799893.2015.1030412 DO - 10.3109/10799893.2015.1030412 ID - Sun2015 ER - TY - JOUR AU - Palomo, J. AU - Dietrich, D. AU - Martin, P. AU - Palmer, G. AU - Gabay, C. PY - 2015 DA - 2015// TI - The interleukin (IL)-1 cytokine family—balance between agonists and antagonists in inflammatory diseases JO - Cytokine. VL - 76 UR - https://doi.org/10.1016/j.cyto.2015.06.017 DO - 10.1016/j.cyto.2015.06.017 ID - Palomo2015 ER - TY - JOUR AU - Striz, I. PY - 2017 DA - 2017// TI - Cytokines of the IL-1 family: recognized targets in chronic inflammation underrated in organ transplantations JO - Clin Sci (London, England : 1979). VL - 131 UR - https://doi.org/10.1042/CS20170098 DO - 10.1042/CS20170098 ID - Striz2017 ER - TY - JOUR AU - Xu, Y. AU - Zhang, P. AU - Liu, Y. PY - 2017 DA - 2017// TI - Chidamide tablets: HDAC inhibition to treat lymphoma JO - Drugs Today. VL - 53 UR - https://doi.org/10.1358/dot.2017.53.3.2595452 DO - 10.1358/dot.2017.53.3.2595452 ID - Xu2017 ER - TY - JOUR AU - Qu, X. AU - Yu, H. AU - Jia, B. AU - Yu, X. AU - Cui, Q. AU - Liu, Z. PY - 2016 DA - 2016// TI - Association of downregulated HDAC 2 with the impaired mitochondrial function and cytokine secretion in the monocytes/macrophages from gestational diabetes mellitus patients JO - Cell Biol Int. VL - 40 UR - https://doi.org/10.1002/cbin.10598 DO - 10.1002/cbin.10598 ID - Qu2016 ER - TY - JOUR AU - Fu, M. AU - Shi, W. AU - Li, Z. AU - Liu, H. PY - 2016 DA - 2016// TI - Activation of mPTP-dependent mitochondrial apoptosis pathway by a novel pan HDAC inhibitor resminostat in hepatocellular carcinoma cells JO - Biochem Biophys Res Commun. VL - 477 UR - https://doi.org/10.1016/j.bbrc.2016.04.147 DO - 10.1016/j.bbrc.2016.04.147 ID - Fu2016 ER - TY - JOUR AU - Shadel, G. S. AU - Horvath, T. L. PY - 2015 DA - 2015// TI - Mitochondrial ROS signaling in organismal homeostasis JO - Cell. VL - 163 UR - https://doi.org/10.1016/j.cell.2015.10.001 DO - 10.1016/j.cell.2015.10.001 ID - Shadel2015 ER - TY - JOUR AU - Sabharwal, S. S. AU - Schumacker, P. T. PY - 2014 DA - 2014// TI - Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel? JO - Nat Rev Cancer. VL - 14 UR - https://doi.org/10.1038/nrc3803 DO - 10.1038/nrc3803 ID - Sabharwal2014 ER - TY - JOUR AU - Kottemann, M. C. AU - Bale, A. E. PY - 2009 DA - 2009// TI - Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model JO - DNA Repair. VL - 8 UR - https://doi.org/10.1016/j.dnarep.2009.06.001 DO - 10.1016/j.dnarep.2009.06.001 ID - Kottemann2009 ER - TY - JOUR AU - Long, J. AU - Fang, W. Y. AU - Chang, L. AU - Gao, W. H. AU - Shen, Y. AU - Jia, M. Y. PY - 2017 DA - 2017// TI - Targeting HDAC3, a new partner protein of AKT in the reversal of chemoresistance in acute myeloid leukemia via DNA damage response JO - Leukemia. VL - 31 UR - https://doi.org/10.1038/leu.2017.130 DO - 10.1038/leu.2017.130 ID - Long2017 ER - TY - JOUR AU - Nikolova, T. AU - Kiweler, N. AU - Krämer, O. H. PY - 2017 DA - 2017// TI - Interstrand Crosslink Repair as a Target for HDAC Inhibition JO - Trends Pharmacol Sci. VL - 38 UR - https://doi.org/10.1016/j.tips.2017.05.009 DO - 10.1016/j.tips.2017.05.009 ID - Nikolova2017 ER - TY - JOUR AU - Carrassa, L. AU - Damia, G. PY - 2017 DA - 2017// TI - DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy JO - Cancer Treat Rev. VL - 60 UR - https://doi.org/10.1016/j.ctrv.2017.08.013 DO - 10.1016/j.ctrv.2017.08.013 ID - Carrassa2017 ER - TY - JOUR AU - Berger, N. D. AU - Stanley, F. K. T. AU - Moore, S. AU - Goodarzi, A. A. PY - 2017 DA - 2017// TI - ATM-dependent pathways of chromatin remodelling and oxidative DNA damage responses JO - Philos Trans R Soc Lond B Biol Sci. VL - 372 UR - https://doi.org/10.1098/rstb.2016.0283 DO - 10.1098/rstb.2016.0283 ID - Berger2017 ER - TY - JOUR AU - Qiu, Z. AU - Oleinick, N. L. AU - Zhang, J. PY - 2018 DA - 2018// TI - ATR/CHK1 inhibitors and cancer therapy JO - Radiother Oncol. VL - 126 UR - https://doi.org/10.1016/j.radonc.2017.09.043 DO - 10.1016/j.radonc.2017.09.043 ID - Qiu2018 ER - TY - JOUR AU - Bolcun-Filas, E. AU - Rinaldi, V. D. AU - White, M. E. AU - Schimenti, J. C. PY - 2014 DA - 2014// TI - Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway JO - Science. VL - 343 UR - https://doi.org/10.1126/science.1247671 DO - 10.1126/science.1247671 ID - Bolcun-Filas2014 ER - TY - JOUR AU - Zan, H. AU - Tat, C. AU - Qiu, Z. AU - Taylor, J. R. AU - Guerrero, J. A. AU - Shen, T. PY - 2017 DA - 2017// TI - Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination JO - Nat Commun. VL - 8 UR - https://doi.org/10.1038/ncomms14244 DO - 10.1038/ncomms14244 ID - Zan2017 ER -