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Table 2 Genomic and functional context of IDOL and pickCompProbes (raw and filtered) libraries

From: Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data

Ā 

pickCompProbes automatic selection: raw

pickCompProbes automatic selection: filtered

IDOL

n = 666 (%)

n = 662 (%)

n = 517 (%)

Genomic context

ā€ƒCpG island

18 (2.7)

17 (2.6)

39 (7.5)

ā€ƒShelves

95 (14.2)

101 (15.3)

76 (14.7)

ā€ƒShores

100 (15)

107 (16.2)

119 (23)

ā€ƒOpen sea

453 (68.1)

437 (66.1)

282 (54.5)

Functional context

ā€ƒTSS1500

72 (10.8)

74 (11.2)

71 (13.7)

ā€ƒTSS200

36 (5.4)

40 (6)

37 (7.2)

ā€ƒ5'UTR

81 (12.2)

80 (12.1)

75 (14.5)

ā€ƒExon1

18 (2.7)

18 (2.7)

19 (3.7)

ā€ƒBody

335 (50.3)

320 (48.3)

246 (47.6)

ā€ƒ3ā€² UTR

46 (6.9)

42 (6.3)

29 (5.6)

ā€ƒIntergenic

146 (21.9)

153 (23.1)

107 (20.1)

ā€ƒEnhancers (Phantom 5)

38 (5.7)

33 (5)

19 (3.7)

ā€ƒDNase hypersensitive sites

436 (65.5)

436 (65.9)

350 (67.7)