Fig. 4
From: Urinary DNA methylation biomarkers for prediction of prostate cancer upgrading and upstaging
DNA methylation of RARB, RASSF1, and GSTP1 as a biomarker of upgrading. a Methylation levels according to ISUP group change in voided urine samples; b methylation levels according to ISUP group change in catheterized urine samples; c comparison of ROC curves of the gene methylation levels in voided urine samples alone and combined with PSA; d comparison of ROC curves of the gene methylation levels in catheterized urine samples alone and combined with PSA. RASSF1 and GSTP1 together are referred to as the two genes. Significant P values are in bold