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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Urinary DNA methylation biomarkers for prediction of prostate cancer upgrading and upstaging

Fig. 3

DNA methylation of RARB, RASSF1, and GSTP1 as a biomarker of upstaging. a Methylation levels according to tumour stage change in voided urine samples; b methylation levels according to tumour stage change in catheterized urine samples; c comparison of ROC curves of the three-gene methylation in voided urine samples alone and combined with PSA; d comparison of ROC curves of the gene methylation in catheterized urine samples alone and combined with PSA; e comparison of ROC curves of the Partin value separately and in combination with the gene methylation in voided urine samples; f comparison of ROC curves of the Partin value separately and in combination with the gene methylation in catheterized urine samples. RASSF1 and GSTP1 together are referred to as the two genes. Significant P values are in bold

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