Fig. 6From: Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC)Kaplan–Meier survival curves for the 344 patients with OSCC from TCGA HNSCC cohort according to the methylation status of the three candidate genes. Overall survival for a GATA4 (cg24910352 located on gene body) and SOX17 (cg04672706 located on promoter region), respectively. b Combination of GATA4 and SOX17 genes methylation (left) and TFPI2 (cg22441533 located on promoter region) and SOX17 genes methylation (right). c Combination of TFPI2, GATA4, and SOX17 genes methylation. Probe positions were annotated using the UCSC genome browser. Clinical information of patients with OSCC (n = 344) were divided into two groups (methylation high group; orange line, n = 172; methylation low group; blue line, n = 172) according to their methylation status (β-values) on TFPI2, SOX17, or GATA4. A probability of <  0.05 (log rank test *p < 0.05) was considered to represent a statistically significant differenceBack to article page