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Table 1 Summary of clinical information for case and control groups enrolled in this study

From: Placenta-specific epimutation at H19-DMR among common pregnancy complications: its frequency and effect on the expression patterns of H19 and IGF2

Case/control group (or case #) Average ± SD
Gestational age (week) Fetal weight (g) Placental weight (g) Fetal weight/placental weight
Set I
 Control group I 1) (n = 39) 38.8 ± 1.3 3002 ± 407 506 ± 129 6.2 ± 1.9
 Case group I 1) (FGR and/or PIH, n = 140) 35.5 ± 4.4 1793 ± 596 277 ± 89 6.5 ± 1.7
 (statistical test p value) (1.59 × 10−8) (1.08 × 10−25) (8.91 × 10−23) (0.289)
 Case 1 (FGR) 30 724 115 6.3
 Case 2 (PIH) 30 1376 213 6.5
Set II
 Control group II 2) (n = 29) 39.1 ± 1.3 3059 ± 311 601 ± 100 5.2 ± 0.8
 Case group II 2) (FGR and/or PIH, n = 62) 35.7 ± 2.6 2017 ± 545 456 ± 127 4.5 ± 1.0
 (statistical test p value) (3.81 × 10−10) (1.00 × 10−25) (3.42 × 10−7) (0.0016)
 Case 3 (PIH) 33 1628 420 3.9
  1. 1)Chorionic plate tissues were collected for all cases and controls. Cord blood samples were collected for subset of cases and controls
  2. 2)Only chorionic villi were collected for all cases and controls