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Fig. 2 | Clinical Epigenetics

Fig. 2

From: Placenta-specific epimutation at H19-DMR among common pregnancy complications: its frequency and effect on the expression patterns of H19 and IGF2

Fig. 2

a–l Comparison of methylation levels of H19-DMR and IGF2-DMRs in FGR, PIH, and control (Con) groups. FGR cases without PIH phenotype and PIH cases with or without FGR phenotype are regarded as FGR and PIH groups, respectively, in this analysis. The numbers of individuals in each group are shown underneath each panel. Statistical significance of difference in DNA methylation levels between FGR or PIH group and a control group was assessed by the Wilcoxon signed-rank test (R version 3.4.4) (Additional file 3: Table S1). P values are shown for the pairs of comparisons for which statistical significance (p < 0.05) was detected

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Clinical Epigenetics

ISSN: 1868-7083

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