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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation signature is prognostic of choroid plexus tumor aggressiveness

Fig. 2

Kaplan–Meier (KM) curve depicting overall survival (OS) estimates of patients with CPT by methylation subgroups. Statistical values comparing the three KM curves were obtained with the log-rank chi-square = 16.7 (df = 2), p value 0.0002; and Wilcoxon–Gehan chi-square = 15.5 (df = 2), p value 0.00043. Group 1 (pink highlight in top panel, red line in KM plot (n = 5)), CPCs with homozygous TP53-mut (mutant) = violet bar; group 2 (blue highlight in top panel, blue line in KM plot (n = 7)), CPCs with heterozygous TP53-mut = orange bar and TP53-wt (wild type) = green bar; group 3 (orange highlight in top panel, orange line in KM plot (n = 22)), CPPs-heterozygous TP53-mut = orange bar and TP53-wt = green bar and two CPCs with TP53-wt = green bar; diagnosis: cpc = red, acpp = pink, cpp = turquoise

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