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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients

Fig. 6

Changes of miR-15a/Bcl2 pathway in SUV39H1-overexpressing ATDC5 cells. a, b The protein and mRNA levels of Bcl2 and Bax in SUV39H1-overexpressing and control ATDC5 cells, n = 6 independent transfection cells. c The expression levels of miR-15a and miR-16 in SUV39H1-overexpressing and control ATDC5 cells, n = 6 independent transfection cells. d The mRNA levels of miR-15a/16 host gene in SUV39H1-overexpressing and control ATDC5 cells, n = 6 independent transfection cells. e The levels of H3K9me3 in the promoter region of miR-15a/16 host gene in SUV39H1-overexpressing and control ATDC5 cells assessed by ChIP assay, n = 3 independent transfection cells. P1––P3, three pairs of primers in the promoter region of miR-15a/16 host gene. #p < 0.05

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