Skip to main content

Advertisement

Table 5 CVD risk models using cumulative risk factor exposure and brown module activation

From: DNA methylation modules associate with incident cardiovascular disease and cumulative risk factor exposure

  Risk factors only Brown only Full model
Risk factor Cumulative Module Cumulative Module
BMI 0.061 (0.009) 0.012 (0.1) 0.057 (0.015) 0.01 (0.16)
hsCRP 0.64 (< 0.001) 0.014 (0.054) 0.62 (< 0.001) 0.012 (0.12)
TG 1.7 (< 0.001) 0.016 (0.039) 1.7 (< 0.001) 0.012 (0.1)
  1. Regression results are presented as beta (p value). Models are adjusted for age, sex, smoking status and pack-years, estimated cell counts, study center, and 7 control probe principal components