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Table 4 Module-risk factor relationships (current and cumulative) after adjustment for covariates

From: DNA methylation modules associate with incident cardiovascular disease and cumulative risk factor exposure

  Brown Blue
Risk factor Current Cumulative Current Cumulative
BMI 0.036 (4.3e −06) 0.051 (2.3e −10) 0.026 (0.0061) 0.019 (0.051)
Glu 0.021 (0.011) 0.027 (0.0011) − 0.00065 (0.95) − 0.0045 (0.66)
hsCRP 0.021 (0.0077) 0.039 (1e −06) 0.025 (0.011) 0.014 (0.15)
TG 0.018 (0.02) 0.042 (5e −07) 0.021 (0.03) 0.015 (0.14)
HDL − 0.021 (0.015) − 0.017 (0.056) − 0.038 (0.00031) − 0.03 (0.0067)
LDL − 0.012 (0.13) 0.0089 (0.29) − 0.00072 (0.94) 0.027 (0.0088)
Chol − 0.014 (0.11) 0.019 (0.021) − 0.013 (0.2) 0.012 (0.24)
SBP 0.012 (0.15) 0.024 (0.0084) − 0.011 (0.27) − 0.0015 (0.89)
  1. Regression results are presented as beta (p value). Models are adjusted for age, sex, smoking status and pack-years, estimated cell counts, study center, and 7 control probe principal components