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Table 3 Comb-p regions with multiple test-corrected p < 0.05 in WHI and Bonferroni p < 0.05 in FHS

From: DNA methylation modules associate with incident cardiovascular disease and cumulative risk factor exposure

    

Discovery

Replication

Location

# CpGs

Annotated gene

Genomic region

p

Adj. P

p

chr1:27440462-27440721

3

SLC9A1

Body

1.75e −08

2.85e −05

1.03e −04

chr19:47287777-47288263

6

SLC1A5

CpG shelf near TSS

5.91e −e-04

3.80e −10

 

chr17:76037034-76037562

6

TNRC6C

CpG island in 5’ UTR

1.67e −05

1.33e −02

1.89e −04

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Clinical Epigenetics

ISSN: 1868-7083

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