Fig. 1From: Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenomeThe TCA cycle occurs predominantly in the mitochondrial matrix, although some reactions can occur beyond the mitochondria, including in the cytoplasm and nucleus. Solid arrows represent the reaction direction (enzymes omitted for simplicity), whilst dashed arrows represent the transport of metabolites into the cytoplasmBack to article page