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Table 3 Results of top ACPC-associated DMRs separated into those where there was a SNP influencing methylation levels nearby (gDMRs) and those where a nearby associated SNP (ngDMRs) was not found

From: Rheumatoid arthritis-relevant DNA methylation changes identified in ACPA-positive asymptomatic individuals using methylome capture sequencing

#chr Start End #DMC q values, mean Methdiff, mean Distance to TSS Gene name
gDMRs
chr10 43140840 43140878 4 4.68E−06 12 − 6574 ZNF33B
chr13 114579169 114579173 4 6.20E−06 15 7288 LINC00454
chr19 13874993 13875015 4 5.42E−05 − 12 − 324 MRI1
chr4 185189026 185189056 4 0.000174 24 − 49,927 ENPP6
chr12 42539166 42539215 8 6.22E−04 11 − 518 GXYLT1
chr12 124858272 124858284 4 1.03E−03 − 11 − 36,490 MIR6880
chr12 11699957 11700234 22 0.00154 − 14 − 868 LINC01252
chr6 26755655 26755778 6 1.98E−03 12 − 95,737 ZNF322
chr5 171203344 171203485 14 2.31E−03 11 − 9461 SMIM23
chr15 91474603 91474621 4 0.00294 − 10 1187 HDDC3
ngDMRs
chr13 114579169 114579173 4 6.20E−06 15 7288 LINC00454
chr14 24944437 24944579 10 8.84E−05 − 12 32,349 LOC101927045
chr2 1370435 1370661 24 4.05E−04 11 − 46,685 TPO
chr12 42539166 42539215 8 6.22E−04 11 − 518 GXYLT1
chr20 29523738 29524187 27 1.42E−03 − 14 46,400 LINC01598
chr2 91850066 91850070 4 1.71E−03 − 16 − 2093 LOC654342
chr6 26755655 26755778 6 1.98E−03 12 − 95,737 ZNF322
chr7 93996387 93996403 6 2.69E−03 − 11 − 27,478 COL1A2
chr15 91474603 91474621 4 0.00294 − 10 1187 HDDC3
chr14 106865983 106866072 4 3.05E−03 − 10 − 72,417 LINC00221