Table 6 Results from the pathway analyses for differentially expressed genes
Pathway | Identifier | Class | p value | q value |
|---|---|---|---|---|
Reactome database | ||||
 The Citric Acid Cycle and Respiratory Electron Transport | R-HSA-1428517 | Metabolism (electron transport) | 1.4 × 10−5 | 0.009 |
 tRNA Aminoacetylation | R-HSA-379724 | Metabolism of proteins | 1.1 × 10−4 | 0.019 |
 Assembly of the pre-Replicative Complex | R-HSA-68867 | DNA replication | 1.3 × 10−4 | 0.019 |
 M-G1-Transition | NA | Cell cycle | 1.4 × 10−4 | 0.019 |
 Cytosolic tRNA Aminoacylation | R-HSA-379716 | Metabolism of proteins | 1.7 × 10−4 | 0.019 |
 HIV-Infection | R-HSA-162906 | Disease | 2.1 × 10−4 | 0.019 |
 Host Interactions of HIV Factors | R-HSA-162909 | Disease | 2.1 × 10−4 | 0.019 |
 Cell Cycle Checkpoints | R-HSA-69620 | Cell Cycle | 3.4 × 10−4 | 0.021 |
 Destabilisation of mRNA by AUF1 (hnRNP D0) | R-HSA-450580 | Metabolism of RNA | 3.5 × 10−4 | 0.021 |
 Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins | R-HSA-163200 | Metabolism (electron transport) | 3.7 × 10−4 | 0.021 |
 CDT1 association with the CDC6:ORC:origin complex | R-HSA-68827 | DNA replication | 3.7 × 10−4 | 0.021 |
 Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins | R-HSA-176409 | Cell cycle | 5.4 × 10−4 | 0.026 |
 Orc1 removal from chromatin | R-HSA-68949 | Cell cycle, DNA replication | 5.7 × 10−4 | 0.026 |
 Regulation of mitotic cell cycle | R-HSA-453276 | Cell cycle | 6.0 × 10−4 | 0.026 |
 Respiratory electron transport | R-HSA-611105 | Metabolism (electron transport) | 6.0 × 10−4 | 0.026 |
 G1/S Transition | R-HSA-69206 | Cell cycle | 7.3 × 10−4 | 0.029 |
 Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | Metabolism | 9.2 × 10−4 | 0.033 |
 CDK-mediated phosphorylation and removal Cdc6 | R-HSA-69017 | Cell cycle, DNA replication | 9.5 × 10−4 | 0.033 |
 Autodegradation of the E3 ubiquitin ligase COP1 | R-HSA-349425 | Cell cycle | 9.8 × 10−4 | 0.033 |
 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | R-HSA-174178 | Cell cycle | 1.2 × 10−3 | 0.038 |
 Metabolism of RNA | R-HSA-8953854 | Metabolism of RNA | 1.3 × 10−3 | 0.038 |
 SCF-beta-TrCP mediated degradation of Emi1 | R-HSA-174113 | Cell cycle | 1.4 × 10−3 | 0.039 |
 Mitotic G1-G1/S phases | R-HSA-453279 | Cell cycle | 1.4 × 10−3 | 0.040 |
 Mitotic M-M/G1 phases | R-HSA-453274 | Cell cycle | 1.5 × 10−3 | 0.040 |
KEGG database | ||||
 Aminoacyl tRNA Biosynthesis | hsa00970 | Translation | 1.9 × 10−4 | 0.034 |
 Metabolism of Xenobiotics by Cytochrome P450 | rn00980 | Metabolism/xenobiotics biodegradation | 3.7 × 10−4 | 0.034 |