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Table 5 Summary of altered CGIs in the different cancer types

From: Clustered protocadherins methylation alterations in cancer

UCSC CGI

Relation to UCSC CGI

Methylation Analyses

CRA

CRC

GC

BTC

PA

CLL

Intrahepatic chol

Extrahepatic chol

Gallbladder cancer

chr5:140750050-140750264

Island

Hypermethylation

NA

NA

NA

NA

NA

ND

NA

chr5:140762401-140762768

Island

NA

NA

Hypermethylation

ND

ND

ND

ND

NA

chr5:140787447-140788044

Island

NA

NA

Hypermethylation

NA

Hypermethylation

Hypermethylation

ND

NA

chr5:140855386-140856620

Island

NA

Hypermethylation

Hypermethylation

NA

NA

NA

NA

NA

chr5:140857864-140858065

Island

Hypermethylation

Hypermethylation

NA

NA

NA

NA

ND

NA

chr5:140864527-140864748

Island

Hypermethylation

Hypermethylation

Hypermethylation

NA

NA

NA

NA

NA

chr5:140871064-140872335

N-shelf

NA

NA

NA

NA

NA

NA

Hypomethylation

NA

chr5:140892914-140893189

Island

Hypermethylation

Hypermethylation

NA

NA

NA

NA

ND

NA

  1. Note: CGI CpG island, CRA colorectal adenoma, CRC colorectal cancer, GC gastric cancer, BTC biliary tract cancer, chol cholangiocarcinoma, PA pilocytic astrocytoma, CLL chronic lymphocytic leukemia, NA no alteration, ND not detected