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Table 5 Summary of altered CGIs in the different cancer types

From: Clustered protocadherins methylation alterations in cancer

UCSC CGI Relation to UCSC CGI Methylation Analyses
CRA CRC GC BTC PA CLL
Intrahepatic chol Extrahepatic chol Gallbladder cancer
chr5:140750050-140750264 Island Hypermethylation NA NA NA NA NA ND NA
chr5:140762401-140762768 Island NA NA Hypermethylation ND ND ND ND NA
chr5:140787447-140788044 Island NA NA Hypermethylation NA Hypermethylation Hypermethylation ND NA
chr5:140855386-140856620 Island NA Hypermethylation Hypermethylation NA NA NA NA NA
chr5:140857864-140858065 Island Hypermethylation Hypermethylation NA NA NA NA ND NA
chr5:140864527-140864748 Island Hypermethylation Hypermethylation Hypermethylation NA NA NA NA NA
chr5:140871064-140872335 N-shelf NA NA NA NA NA NA Hypomethylation NA
chr5:140892914-140893189 Island Hypermethylation Hypermethylation NA NA NA NA ND NA
  1. Note: CGI CpG island, CRA colorectal adenoma, CRC colorectal cancer, GC gastric cancer, BTC biliary tract cancer, chol cholangiocarcinoma, PA pilocytic astrocytoma, CLL chronic lymphocytic leukemia, NA no alteration, ND not detected