Table 4 Altered CGIs in biliary tract cancer
From: Clustered protocadherins methylation alterations in cancer
UCSC CGI | UCSC CGI name | CTCF binding site | Δβ value (BTC-control) | Δβ value (Intrahepatic chol-control) | Δβ value (Extrahepatic chol-control) | Δβ value (Gallbladder cancer-control) | Δβ value (Extrahepatic/gallbladder-control) | Genes within region | Gene promoter-associated CGI |
|---|---|---|---|---|---|---|---|---|---|
chr5:140787447-140788044 | CpG 45 | chr5:140786247-140788714 | 0.175 | 0.104 | 0.212 | 0.235 | 0.229 | PCDHGA1, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6 | PCDHGB6 |
chr5:140797162-140797701 | CpG 41 | chr5:140795962-140798360 | 0.130 | 0.108 | 0.200 | 0.215 | 0.209 | PCDHGA1, PCDHGA10, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7 | PCDHGB7 |