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Table 2 Altered CGIs in colorectal cancer and colorectal adenoma

From: Clustered protocadherins methylation alterations in cancer

UCSC CGI UCSC CGI name CTCF binding site Δβ value (CRC-control) Δβ value (CRA-control) Genes within region Gene promoter-associated CGI
chr5:140750050-140750264 CpG 16 chr5:140748521-140750945 0.157* 0.200 PCDHGA1, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGB1, PCDHGB2, PCDHGB3 PCDHGB3
chr5:140855386-140856620 CpG 95 chr5:140854218-140856648 0.200* 0.105 PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3 PCDHGC3
chr5:140857864-140858065 CpG 19 chr5:140856882-140859319 0.310 0.259 PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3
chr5:140864527-140864748 CpG 22 0.435 0.277 PCDHGA1, PCDHGA10, PCDHGA11, PCDHGA12, PCDHGA2, PCDHGA3, PCDHGA4, PCDHGA5, PCDHGA6, PCDHGA7, PCDHGA8, PCDHGA9, PCDHGB1, PCDHGB2, PCDHGB3, PCDHGB4, PCDHGB5, PCDHGB6, PCDHGB7, PCDHGC3, PCDHGC4 PCDHGC4
chr5:140892914-140893189 CpG 20 chr5:140890901-140893291 0.302 0.200
chr5:140891594-140893806
  1. Note: CGI CpG island, CRC colorectal cancer, CRA colorectal adenoma. *Nominal threshold (p value < 0.05). CpG 16, 95, 19, 22 and 20 correspond to UCSC CGI name