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Table 3 Multivariate Cox proportional hazards analysis of BCR-free survival in TCGA cohort including PC patients treated by radical prostatectomy

From: SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy

Variable P value Hazard ratio [95% CI]
cg19788741 (continuous) 0.087 3.927 [0.815, 18.904]
 pT3-4 vs. pT2 0.031 3.843 [1.123, 13.154]
 pN1 vs. pN0 0.968 0.987 [0.516, 1.886]
 Gleason score 0.009 2.587 [1.267, 5.280]
 Preoperative PSA 0.051 1.018 [0.999, 1.036]
cg06480736 (continuous) 0.049 1.809 [1.175, 13.769]
 pT3-4 vs. pT2 0.026 4.022 [2.617, 20.172]
 pN1 vs. pN0 0.993 1.002 [0.525, 1.941]
 Gleason score 0.011 2.528 [1.234, 5.179]
 Preoperative PSA 0.064 1.016 [0.999, 1.034]
cg19774478 (continuous) 0.041 1.903 [1.025, 3.534]
 pT3-4 vs. pT2 0.045 3.532 [1.023, 12.199]
 pN1 vs. pN0 0.826 0.092 [0.485, 1.780]
 Gleason score 0.005 2.744 [1.344, 5.602]
 Preoperative PSA 0.047 1.018 [1.000, 1.037]
cg22149516 (continuous) 0.008 2.316 [1.233, 4.350]
 pT3-4 vs. pT2 0.040 3.662 [1.055, 12.710]
 pN1 vs. pN0 0.972 1.011 [0.530, 1.927]
 Gleason score 0.018 2.385 [1.155, 4.925]
 Preoperative PSA 0.031 1.019 [1.001, 1.037]