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Table 3 Multivariate Cox proportional hazards analysis of BCR-free survival in TCGA cohort including PC patients treated by radical prostatectomy

From: SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy

Variable

P value

Hazard ratio [95% CI]

cg19788741 (continuous)

0.087

3.927 [0.815, 18.904]

 pT3-4 vs. pT2

0.031

3.843 [1.123, 13.154]

 pN1 vs. pN0

0.968

0.987 [0.516, 1.886]

 Gleason score

0.009

2.587 [1.267, 5.280]

 Preoperative PSA

0.051

1.018 [0.999, 1.036]

cg06480736 (continuous)

0.049

1.809 [1.175, 13.769]

 pT3-4 vs. pT2

0.026

4.022 [2.617, 20.172]

 pN1 vs. pN0

0.993

1.002 [0.525, 1.941]

 Gleason score

0.011

2.528 [1.234, 5.179]

 Preoperative PSA

0.064

1.016 [0.999, 1.034]

cg19774478 (continuous)

0.041

1.903 [1.025, 3.534]

 pT3-4 vs. pT2

0.045

3.532 [1.023, 12.199]

 pN1 vs. pN0

0.826

0.092 [0.485, 1.780]

 Gleason score

0.005

2.744 [1.344, 5.602]

 Preoperative PSA

0.047

1.018 [1.000, 1.037]

cg22149516 (continuous)

0.008

2.316 [1.233, 4.350]

 pT3-4 vs. pT2

0.040

3.662 [1.055, 12.710]

 pN1 vs. pN0

0.972

1.011 [0.530, 1.927]

 Gleason score

0.018

2.385 [1.155, 4.925]

 Preoperative PSA

0.031

1.019 [1.001, 1.037]