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Table 2 Univariate Cox proportional hazards analysis of BCR-free survival in TCGA cohort including PC patients treated by radical prostatectomy

From: SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy

Variable P value Hazard ratio [95% CI]
Age (> 60 vs. ≤ 60) 0.8385 0.944 [0.545, 1.637]
pT3-4 vs. pT2 < 0.001 7.266 [2.617, 20.172]
pN1 vs. pN0 0.025 2.045 [1.094, 3.823]
Gleason score < 0.001 4.244 [2.256, 7.981]
Preoperative PSA 0.0015 1.025 [1.009, 1.04]
R1 vs. R0 0.0231 1.902 [1.092, 3.312]
SLCO4C1 methylation
 cg06480736 (continuous) < 0.001 15.914 [3.863, 65.565]
 cg19774478 (continuous) < 0.001 9.001 [2.789, 29.054]
 cg19788741 (continuous) 0.003 10.759 [2.203, 52.553]
 cg22149516 (continuous) 0.006 17.144 [2.295, 128.066]