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Table 1 Correlation between SLCO4C1 DNA promoter methylation and clinicopathological parameters

From: SLCO4C1 promoter methylation is a potential biomarker for prognosis associated with biochemical recurrence-free survival after radical prostatectomy

Variable All patients cg22149516 (P value) cg06480736 (P value) cg19788741 (P value) cg19774478 (P value)
Patient number 498     
Age (years)
 > 60 247     
 ≤ 60 251 0.09a 0.04a 0.03a 0.36a
Tumour category
 pT2 188     
 pT3 and pT4 303     
 Unknown 7 0.02a < 0.01a < 0.01a < 0.01a
Gleason score
 < 7 45     
 3 + 4 147     
 4 + 3 101     
 = 8 64     
 > 8 141 0.28a < 0.01a < 0.01a < 0.01a
Surgical margin
 R0 316     
 R1, R2 and RX 162     
 Unknown 20 0.06a < 0.01a < 0.01a 0.02a
Nodal category
 pN0 346     
 pN1 79     
 Unknown 73 0.18a 0.02a 0.01a 0.01a
Preoperative PSA [ng/ml]
 0~4 51     
 4–10 286     
 > 10 153     
 Unknown 8 0.64b 0.28b 0.42b 0.25b
  1. aMann-Whitney U test
  2. bKruskal-Wallis test