Fig. 2From: Parent-of-origin-specific allelic expression in the human placenta is limited to established imprinted loci and it is stably maintained across pregnancyExamples of analyzed candidate imprinted genes stratified based on the proportions of transcribed parental alleles. A gene was confirmed as imprinted, when it was expressed in a high-confidence parent-of-origin-specific manner (binomial test, Pcorr < 0.05; > 90% transcripts originating from one parental allele). Biased parental allelic expression was defined when a significant deviation from the equal proportions of transcribed parental alleles was observed, but it did not correspond to exclusive monoallelic transcription (binomial test, Pcorr < 0.05; 65–90% of reads from one parental allele). A gene was confirmed as biallelically expressed when the proportions of parental reads did not differ significantly from the expected ratio (Pcorr > 0.05) and/or the estimated proportions of both parental allelic reads fall within 35–65%. Detailed information on all analyzed genes is provided in Additional file 8: Table S6 and in the assembled gene-based catalog (Additional file 9: Figure S2), including data of parental allelic proportions and expression for all analyzed clinical subgroups. GD, gestational diabetes; LGA, large-for-gestational-age newborn; PE, preeclampsia; SGA, small-for-gestational-age newborn; Trim, trimesterBack to article page