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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)

Fig. 4

MCTA-Seq deconvolution analysis of healthy individuals and liver disease patients. a Boxplots showing absolute (upper panel) or fractional (lower panel) DNA fractions derived from different tissues in healthy individuals. b Boxplots showing absolute liver DNA fractions in the plasma of healthy individuals and liver disease patients. ***P < 0.01; nd, no difference. c A heatmap showing the methylation of tissue-specific CGCGCGG markers in plasma samples obtained from the cholelithiasis patients. The asterisks indicate two hepatolithiasis patients

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