DNA methylation changes related to nutritional deprivation: a genome-wide analysis of population and in vitro data

Table 2 Three DMRs consistently associated with famine in both experiments (Chinese famine samples and fibroblasts samples)

DMRs	Gene promoters	CHR	Region (hg19)	CpG numbers	β value (Chinese)	p value (Chinese)	β value (Fibroblasts)	p value (Fibroblasts)
DMR1	ENO2	chr12	7023752–7024121	4	− 0.0243	1.19E−04	− 0.1523	7.42E−04
DMR2	ZNF226	chr19	44669146–44669354	5	− 0.0636	9.21E−03	− 0.3155	1.07E−03
DMR3	CCDC51	chr3	48481268–48481793	13	− 0.0290	7.87E−04	− 0.2318	1.25E−06
DMR3	TMA7	chr3	48481268–48481793	13	− 0.0290	7.87E−04	− 0.2318	1.25E−06

DMR differentially methylated regions, CHR chromosome, hg19 human genome version 19. The first column of the table shows the DMR identifier and followed by the gene name which belongs to the DMR. The chromosome of the gene is provided and followed by the more precise region in hg19 (human genome version 19). The number of significant CpGs response to nutrition deprivation in both studies is presented, and β value and p value of DMRs in both studies are also presented. β value in each study refers to the mean β values of identified CpG in each DMR

ISSN: 1868-7083