| |
Age- and sex-adjusted model*
|
P
interaction
†
|
Fully adjusted model**
|
P
interaction
§
|
---|
| |
Beta( SE)
|
P
|
Beta (SE)
|
P
|
---|
LDL-C
|
Overall
|
0.70 (0.44)
|
0.12
|
0.50
|
0.63 (0.44)
|
0.15
|
0.64
|
|
Male
|
0.24 (0.79)
|
0.76
|
0.22 (0.76)
|
0.77
|
|
Female
|
0.89 (0.55)
|
0.11
|
0.71 (0.55)
|
0.20
|
HDL-C
|
Overall
|
0.20 (0.18)
|
0.27
|
0.87
|
0.17 (0.18)
|
0.35
|
0.97
|
|
Male
|
0.16 (0.31)
|
0.60
|
0.17 (0.33)
|
0.60
|
|
Female
|
0.22 (0.23)
|
0.34
|
0.11 (0.23)
|
0.64
|
logTG
|
Overall
|
0.18 (0.28)
|
0.52
|
0.46
|
0.14 (0.29)
|
0.63
|
0.38
|
|
Male
|
− 0.12 (0.56)
|
0.83
|
− 0.21 (0.56)
|
0.71
|
|
Female
|
0.31 (0.30)
|
0.31
|
0.39 (0.31)
|
0.22
|
Total cholesterol
|
Overall
|
1.09 (0.49)
|
0.03
|
0.70
|
0.94 (0.48)
|
0.05
|
0.79
|
|
Male
|
0.84 (0.91)
|
0.36
|
0.66 (0.89)
|
0.46
|
|
Female
|
1.20 (0.57)
|
0.04
|
1.00 (0.58)
|
0.09
|
- LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, logTG logarithmically transformed triglycerides, SE standard error
- *Adjusted for age and sex among the overall sample; when stratified by gender, age was adjusted among male and female, respectively
- †Assessed by adding an interaction term, gender × CpG1 to the age- and sex-adjusted model among the overall participants
- **Adjusted for age, sex, smoking, drinking, and education level among the overall sample; when stratified by gender, age, smoking, drinking, and education level were adjusted among male and female, respectively
- §Assessed by adding an interaction term, gender × CpG1 to the fully adjusted model among the overall participants