Prenatal adverse environment is associated with epigenetic age deceleration at birth and hypomethylation at the hypoxia-responsive EP300 gene

Table 2 List of CpG sites included in the array located in the EP300 gene and its surrounding CpG island and antisense ncRNA (EP300-AS1)

CpG probe	Genomic coordinates	beta	p value
cg00500400	41487283	0.001	0.67
cg04452260	41487569	0.003	0.09
cg09331127	41487734	− 0.0006	0.79
cg02046995	41487740	0.004	0.49
cg24349919	41487761	0.005	0.09
cg02107564	41488750	− 0.005	0.48
cg03427564	41489051	0.004	0.21
cg03656483	41490340	− 0.001	0.65
cg00187244	41492007	0.011	0.23
cg11931284	41492370	0.015	0.07
cg13028324	41501680	− 0.0005	0.89
cg20730595	41513219	− 0.001	0.85
cg17439569	41513539	− 0.005	0.16
cg05997318	41542772	− 0.014	0.12
cg06793497	41542898	0.021	0.00008
cg06329185	41544246	− 0.0008	0.75
cg07345240	41556691	0.002	0.73
cg25299898	41563501	0.003	0.74
cg12968540	41572924	0.009	0.008
cg26901641	41573032	− 0.006	0.12
cg03950371	41573046	− 0.003	0.48
cg14455139	41573155	− 0.0001	0.98
cg05601844	41573176	− 0.0005	0.89
cg19011939	41591607	− 0.01	0.01
cg12917725	41592634	0.002	0.76
cg25888227	41593581	0.004	0.07
cg22037654	41593650	0.0001	0.94

DNA methylation at CpG sites highlighted in italics was significantly associated with CPR measured during the third trimester in an intrapair approach

ISSN: 1868-7083