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Table 2 Correlation analysis of differentially methylated CpG sites and PAH concentrations in maternal serum

From: Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

CpG sites N Total PAHs, ng/g lipid L_PAHs, ng/g lipid H_PAHs, ng/g lipid
ρ p ρ p ρ p
CASP8_CpG_1 56 − 0.242 0.072 − 0.221 0.102 − 0.275 0.040
CASP8_CpG_2 58 − 0.275 0.037 − 0.257 0.051 − 0.290 0.027
CASP8_CpG_3 58 − 0.212 0.109 − 0.182 0.171 − 0.255 0.053
CASP8_CpG_4 58 − 0.250 0.058 − 0.212 0.111 − 0.296 0.024
CASP8_CpG_5 58 − 0.165 0.216 − 0.125 0.352 − 0.228 0.086
CASP8_CpG_6 58 0.011 0.937 0.061 0.650 − 0.101 0.450
CASP8_CpG_7 56 − 0.157 0.247 − 0.136 0.319 − 0.201 0.137
CASP8_average 58 − 0.239 0.071 − 0.199 0.134 − 0.299 0.023
  1. Note: PAHs, polycyclic aromatic hydrocarbons; total PAHs, sum of all PAHs; L_PAHs, sum of low-molecular-weight PAHs, including acenaphthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, and retene; H_PAHs, sum of high-molecular-weight PAHs, including pyrene, benz[a]anthracene, chrysene, benzo[b]fluoranthene, benzo[k]fluoranthene, and benzo[a]pyrene; ρ, Pearson’s correlation coefficient.