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Table 2 LncRNAs axis associated with neuropathic pain

From: Functional roles of lncRNAs and its potential mechanisms in neuropathic pain

LncRNAs

Target gene

TFs or relevant factors moleculars

Model

Ref.

Kcra2 AS RNA

Kcna2 mRNA

–

SNL and CCI rat model

31,32,33,34

XIST

miR-137

TNFAIP1

CCI rat model

36

XIST

miR-150

ZEB1

CCI rat model

37

XIST

miR-34a

–

CCI rat model

38

XIST

miR-544

STAT3

CCI rat model

39

XIST

miR-154-5p

TLR5

CCI rat model

40

XIST

miR-494

STAT3

CCI rat model

41

uc.48+

P2X7 receptor

p-ERK1/2

Diabetic rat model

47

uc.48+

P2X7 receptor

p-ERK1/2

TN rat model

52

uc.48+

P2X3 receptor

–

Diabetic rat model

48

NONRATT021972

P2X7 receptor

–

Diabetic rat model

46,50

NONRATT021972

P2X3 receptor

ERK1/2, p-ERK

Diabetic rat model

49

BC168687

P2X7 receptor

NO

DNP rat model

53

BC168687

P2X7, TRPV1receptor

TNF-α, IL-1β/p-ERK, p-p38

DNP rat model

54

MRAK009713

P2X3 receptor

–

CCI rat model

55

DGCR5

miR-330-3p

PDCD4

CCI rat model

56

MALAT1

miR-206

ZEB2

CCI rat model

57

LINC00657

miR-136

ZEB1

CCI rat model

58

NEAT1

miR-381

HMGB1

CCI rat model

59

FKBP51

–

–

CCI rat model

60

CCAT1

miR-155

SGK3

bCCI rat model

61

  1. SNL spinal nerve ligation, bCCI bilateral chronic constriction injury, CCI chronic constriction injury, DNP diabetic neuropathic pain, TN trigeminal neuralgia, TFs transcription factors, NGF nerve growth factor, BDNF brain-derived neurotrophic factor