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Fig. 7 | Clinical Epigenetics

Fig. 7

From: UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells

Fig. 7

UHRF1 depletion and HDAC inhibition induce significant changes in the gene expression profiles of CRC cells. a Heat map showing the expression of genes altered by UHRF1 depletion and HDAC inhibition in DLD1 cells. Cells were transfected with the indicated siRNAs and incubated for 48 h, after which the cells were treated with or without TSA for 24 h, and gene expression microarray analysis was performed. b Gene ontology analysis of the selected genes shown in a. c Pathway analysis of the selected genes in a. d Heat map showing the expression of cell cycle-related genes

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