Table 1 Demographic, clinical, and environmental exposure characteristics of cancer patients from the German laryngeal cancer study
Parameters | Category | Patients with tumor tissue, N (%) | Median follow-up time1, years | Patients with adjacent normal tissue, N (%) | Median follow-up time1, years |
|---|---|---|---|---|---|
Total | 181 (100) | 8.5 | 75 (100) | 8.2 | |
Vital status2 | Deceased | 112 (61.9) | 4.8 | 46 (61.3) | 4.1 |
Censored | 64 (35.4) | 12.0 | 28 (37.3) | 12.2 | |
Gender | Male | 167 (92.3) | 8.3 | 72 (96.0) | 8.1 |
Female | 14 (7.7) | 10.8 | 3 (4.0) | 11.4 | |
Age | Under 50 | 12 (6.6) | 10.7 | 6 (8.0) | 11.0 |
50 to < 60 | 54 (29.8) | 11.2 | 23 (30.7) | 12.0 | |
60 to < 70 | 70 (38.7) | 7.2 | 30 (40.0) | 5.7 | |
Over 70 | 45 (24.9) | 7.0 | 16 (21.3) | 4.2 | |
Tumor location | Glottic | 111 (61.3) | 10.3 | 47 (62.7) | 9.2 |
Supraglottic | 48 (26.5) | 5.4 | 19 (25.3) | 8.1 | |
Subglottic | 5 (2.8) | 7.2 | 1 (1.3) | 4.1 | |
Transglottic | 11 (6.1) | 5.0 | 7 (9.3) | 2.1 | |
Unknown | 6 (6.1) | – | 1 (1.3) | – | |
Tumor stage3 | I | 68 (37.6) | 10.8 | 29 (38.7) | 8.4 |
II | 47 (26.0) | 10.5 | 22 (29.3) | 11.0 | |
III | 21 (11.6) | 6.3 | 11 (14.7) | 8.1 | |
IV | 38 (21.0) | 3.5 | 12 (16.0) | 5.1 | |
Recurrences3 | 0 | 134 (74.0) | 9.0 | 50 (66.7) | 9.1 |
1+ | 43 (27.8) | 7.1 | 24 (32.0) | 7.1 | |
Second primary tumors3 | 0 | 151 (83.4) | 9.1 | 64 (85.3) | 9.4 |
1+ | 25 (13.8) | 5.4 | 10 (13.3) | 3.8 | |
Smoking (pack-years) | 0 | 8 (4.4) | 10.0 | 4 (5.3) | 8.4 |
≤ 20 | 21 (11.6) | 11.6 | 9 (12.0) | 11.8 | |
> 20 to ≤ 40 | 64 (35.4) | 9.0 | 28 (37.3) | 6.3 | |
> 40 | 88 (48.6) | 7.5 | 34 (45.3) | 8.7 | |
Alcohol consumption (g ethanol/day) | ≤ 25 | 53 (29.3) | 10.1 | 21 (28.0) | 11.0 |
> 25 to ≤ 75 | 67 (37.0) | 8.0 | 33 (44.0) | 7.1 | |
> 75 | 61 (33.7) | 8.6 | 21 (28.0) | 8.0 |