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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Epigenome-wide association study for lifetime estrogen exposure identifies an epigenetic signature associated with breast cancer risk

Fig. 3

Meta-analysis of the association between MI and breast cancer risk. The association between MI and risk for breast cancer, as a continuous variable (a) or as a categorical variable (b), was estimated in the four studies included in the meta-analysis using conditional logistic regression adjusted for age, BMI, alcohol consumption, and smoking duration (all variables reported at recruitment) and WBC composition. The log odds ratios were combined in a meta-analysis using restricted-maximum likelihood model. The square boxes represent the odds ratios (ORs) and the lines the 95% confidence intervals (CIs). aEPIC-Italy corresponds to the new EPIC-Italy samples, not included in the development of the MI

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