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Fig. 8 | Clinical Epigenetics

Fig. 8

From: Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

Fig. 8

Effects of MC3353 on E-cadherin and MMP2 protein expression levels in PC-3 cancer cells. Cells were treated with vehicle (DMSO) used as control (CTR) or MC3353 for 24 h. a E-cadherin and MMP2 protein detection by western blot. GAPDH was used as a loading control. Blots are representative of three independent experiments. b Densitometric analysis of E-cadherin and MMP2 protein expression. Significance is represented as *p < 0.05 related to the control groups. Data were obtained from three independent experiments and expressed as mean ± SEM

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